Publications by authors named "Lulu L Cheng"

Aim: To report the outcomes of anterior vitrectomy using high speed cutter for scleral fixated intraocular lens (SFIOL) implantation in patients with posterior capsular rupture.

Methods: Medical records of 51 patients with posterior capsular rupture who received high speed cutter anterior vitrectomy limbal incision with SFIOL implantation from June 2011 to December 2013 were reviewed retrospectively for visual outcomes and complications.

Results: Totally 51 eyes of 51 patients were identified (23 males and 28 females).

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Background/aims: To compare the long-term outcomes of primary pterygium surgery with combined conjunctival rotational autograft and mitomycin C (CRA-MMC), mitomycin C alone (MMC) and limbal conjunctival autograft (LCAU).

Methods: The outcomes of primary pterygium excision followed by conjunctival rotational autograft (CRA) combined with intraoperative 0.02% MMC for 5 min (group 1, CRA-MMC, n=61) were compared with historical control groups consisting of, pterygium excision with MMC (group 2, n=47), and, pterygium excision with limbal conjunctival autograft (LCAU) (group 3, n=29).

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The purpose of this study was to assess the long-term outcome of patients with symptomatic bullous keratopathy after amniotic membrane transplant. A retrospective cohort study includes that 20 patients with symptomatic bullous keratopathy, who have underwent amniotic membrane transplant at the Department of Ophthalmology & Visual Sciences, The Chinese University of Hong Kong, Prince of Wales Hospital & Alice Ho Miu Ling Hospital, Hong Kong between 04/1998 and 06/2011, were invited back. Clinical examination was performed, including, pain score assessment (pain score out of 10), epithelial healing, and vision.

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Background: Endothelial keratoplasty (EK) is used increasingly for the management of cases with endothelial dysfunction. Long-term outcomes of the surgery are not widely reported in the literature. We report our experience of EK in Chinese eyes at a University teaching hospital.

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Purpose: Implantation of a scleral-fixated intraocular lens (SFIOL) for the surgical management of aphakia in the absence of capsular support is a safe procedure with a low risk of complications in the early postoperative period. However, data on long-term functional outcome are limited. The purpose of this study is to assess the long-term outcome and complication profile of SFIOL implantation in a cohort of Chinese patients.

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Objective: To compare the long-term outcome of pterygium surgery and the long-term effect on endothelial counts after mitomycin C (MMC) or limbal conjunctival autograft (LCAU) in pterygium surgery.

Design: We performed a 10-year follow-up study of a randomized controlled trial.

Participants: A total of 115 eyes of 114 patients with primary pterygium were treated with intraoperative MMC (n = 63) or LCAU transplants (n = 52).

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Penetrating keratoplasty is the replacement of a diseased cornea with a full-thickness donor graft. In the last century, this 'gold standard' procedure was long established as the treatment of choice for various corneal diseases. The classical indications for a penetrating keratoplasty entailed optical, tectonic, therapeutic, and cosmetic issues.

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Purpose: To report the occurrence and management of recurrent hemorrhage after Descemet stripping endothelial keratoplasty (DSEK) in a patient with pseudophakic bullous keratopathy.

Methods: An 84-year-old Chinese woman on two oral antiplatelet drugs underwent DSEK in her left eye. Preoperative best-corrected visual acuity was 20/30 OD and 14/200 OS.

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Article Synopsis
  • This study aimed to compare the safety of diferentes cephalosporins used during cataract surgery.
  • 129 patients participated, being randomly assigned to receive one of three cephalosporins (cefazolin, cefuroxime, or ceftazidime) or a control (normal saline), with effects measured on eye health post-surgery.
  • Results showed no significant differences in endothelial cell density or retinal thickness between the cephalosporin group and the control, suggesting these antibiotics are safe to use in this surgical context.
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Article Synopsis
  • The study explores the effectiveness of combining conjunctival rotational autograft (CRA) with 0.02% mitomycin C (MMC) for treating primary pterygium, aiming to assess its safety and recurrence rates.
  • A total of 67 patients were observed over at least one year, revealing only 3% recurrence, significantly lower than MMC alone, suggesting CRA-MMC is more effective while also comparable to traditional autografts.
  • The primary postoperative issue was cosmetic graft injection in 61% of cases, yet the procedure was deemed a safe alternative for patients where conventional grafting wasn't possible.
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  • This case report discusses a rare condition called paraneoplastic pemphigus (PNP), which can cause serious eye issues like cicatrising conjunctivitis.
  • Despite initially being misdiagnosed as a drug reaction and not improving after stopping chemotherapy, the patient was later confirmed to have PNP and treated with a combination of oral steroids and intravenous immunoglobulin.
  • The patient's eye condition stabilized, leading to a full recovery of vision, highlighting the importance of prompt treatment to prevent serious complications, while noting an unusual eosinophilic response that is more typical of allergic reactions rather than classical PNP.
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Purpose: To study the relationship between pupil size and light intensity using the Procyon pupillometer.

Setting: University based clinic.

Methods: In this retrospective study, 20 consecutive patients had pupil size assessment with the Procyon pupillometer under 3 different light conditions--4, 0.

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Purpose: To report the in vivo confocal microscopic findings of posterior polymorphous endothelial dystrophy (PPED).

Methods: Four patients with PPED from 2 unrelated families and 2 asymptomatic children of an index patient were included in this observational case series. The eyes of the 6 subjects were examined by confocal light microscopy.

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A 46-year-old man developed surgically induced necrotizing scleritis (SINS) 7 months following uneventful primary bare sclera pterygium excision. The patient underwent two scleral patch grafts for SINS but despite the use of cyclophosphamide and azathioprine, the scleral patch grafts failed within 1 month of surgery on both occasions. Tacrolimus was used for his third scleral patch graft.

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A 56-year-old Chinese man diagnosed with Thygeson's keratitis by clinical biomicroscopy was examined using a tandem scanning confocal microscope. Among normal superficial epithelial cells, clumps of markedly enlarged epithelial cells were identified. Multiple highly reflective filamentary structures were observed in the deeper layers.

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Objective: Orthokeratology is a process by which the corneal curvature is flattened by sequentially fitting rigid gas permeable contact lenses of decreasing central curvature. There has been a resurgence of interest with the recent introduction of reverse geometry lenses. Although promising results have been described in reducing the myopic refractive error, the use of these lenses can be associated with corneal problems, as reported in this case series.

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Purpose: To report a case of orthokeratology lens-related Pseudomonas corneal ulcer in an adult.

Methods: Case report.

Results: A 37-year-old man presented with a 1-day history of painful red eye.

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Purpose: To describe bilateral conjunctival chemosis and central serous chorioretinopathy in a patient with graft-vs-host disease after bone marrow transplant.

Design: Interventional case report.

Methods: A 45-year-old Chinese woman developed blurring of vision 16 days after bone marrow transplant for multiple myeloma.

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Objective: To analyze surgical outcomes of primary rhegmatogenous retinal detachment in high myopes.

Materials And Methods: Medical records of 201 patients who underwent vitreoretinal surgeries for primary retinal detachments were reviewed. Fifty-two eyes of 51 patients with at least 5.

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