Publications by authors named "Lulu Fundikira"

Article Synopsis
  • - Non-ischemic dilated cardiomyopathy (NIDCM) is a leading cause of heart failure, affecting approximately 1 in 2,500 people in developed nations, yet its impact in Tanzania is not well-documented.
  • - A study of 402 NIDCM patients in Tanzania revealed that the majority were male, with a median age of 55, and common symptoms included dyspnea and advanced heart failure, as indicated by a low average ejection fraction of 29.4%.
  • - Findings showed that most cases were linked to hypertension, but the use of recommended medications was low, highlighting a gap in optimal treatment practices among these patients.
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  Prevalence of DCM varies widely in SSA.Cardiovascular risk factors are important in patients with DCM.The role of genetics in idiopathic DCM is not studied in major part of SSA.

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Background: Women with breast cancer in sub-Saharan Africa are commonly diagnosed at advanced stages. In Tanzania, more than 80% of women are diagnosed with stage III or IV disease, and mortality rates are high. This study explored factors contributing to delayed diagnostic evaluation among women with breast cancer in Tanzania.

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Introduction: Despite advances in diagnostic and treatment, morbidity and mortality due to infective endocarditis (IE) has not decreased. There is a discrepancy in epidemiology of IE between developed and developing countries. Over the last years, increased early detection and consequently prevalence of rheumatic heart disease (RHD) and congenital heart disease (CHD) which are considered predisposing conditions for IE, is noted.

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Aims: The histopathology of mitral valve (MV) tissues have been reported in necropsy and retrospective studies. We prospectively studied the histopathological changes in rheumatic mitral stenosis using advanced techniques and corroborated these with clinical presentation, pathogenesis, and management.

Methods: From January 2020 to February 2021, surgically excised rheumatic stenotic MV from 54 Tanzanian patients were studied.

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Background: Cardiomyopathies, defined as diseases involving mainly the heart muscles, are linked to an estimated 5.9 of 100,000 deaths globally. In sub-Saharan Africa, cardiomyopathies constitute 21.

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