International regional competitiveness of rural territories as a factor of their socio-economic development: Methodological aspects.

The study aims to develop a scientific and methodological approach to the formation of a model for managing the international competitiveness of rural areas based on an assessment of the existing export and production potential to form priorities for their socio-economic development. Research methods involve a systematic approach, an integrated approach, an algorithmization using methods of integral assessment of competitiveness, etc. The research allowed the development of a conceptual model for managing the international competitiveness of rural regions.

A Modern Look at Spiropyrans: From Single Molecules to Smart Materials.

Photochromic compounds of the spiropyran family have two main isomers capable of inter-switching with UV or visible light. In the current review, we discuss recent advances in the synthesis, investigation of properties, and applications of spiropyran derivatives. Spiropyrans of the indoline series are in focus as the most promising representatives of multi-sensitive spirocyclic compounds, which can be switched by a number of external stimuli, including light, temperature, pH, presence of metal ions, and mechanical stress.

Scenario Method of Strategic Planning and Forecasting the Development of the Rural Economy in Agricultural Complex.

The purpose of the study is to justify the use of the universal scenario method of strategic planning and forecasting the development of the agroindustrial complex of the regional rural economy. The scientific novelty of the study lies in the application of a set of theoretical and methodological provisions for scenario planning and forecasting the development of agriculture in the regions, taking into account the assessment of their existing potential and constructing a territorial planning scheme for the priority of participation in the implementation of strategic directions of rural development in agricultural production. The paper presents a territorial model of the priority of participation of the municipal regions of the Republic of Bashkortostan in the implementation of strategic areas in the areas of development of production of grain crops, sugar beet, and oilseeds.

The insulator functions of the polydactyl C2H2 zinc finger protein CTCF: Necessity versus sufficiency.

In mammals, a C2H2 zinc finger (C2H2) protein, CTCF, acts as the master regulator of chromosomal architecture and of the expression of Hox gene clusters. Like mammalian CTCF, the homolog, dCTCF, localizes to boundaries in the bithorax complex (BX-C). Here, we have determined the minimal requirements for the assembly of a functional boundary by dCTCF and two other C2H2 zinc finger proteins, Pita and Su(Hw).

Strategic Planning of Rural Development Based on Foresight Methodologies.

The purpose of the study is to establish scientific rational for the use of the foresight methodology in the strategic planning of rural development. The scientific novelty of the study is determined by the development of an algorithm for strategic planning of rural development based on the foresight methodology and by the formation of a set of practical recommendations for the use of foresight tools at the municipal level of management in rural areas. The paper states that modern foresight methodology is quite flexible and multifaceted.

Visible to near-IR molecular switches based on photochromic indoline spiropyrans with a conjugated cationic fragment.

Photochromic molecules which can absorb and emit light within the "biological window" (650-1450 nm) are of great interest for using in various important biomedical applications such as bio-imaging, photopharmacology, targeted drug delivery, etc. Here we present three new indoline spiropyrans containing conjugated cationic fragments and halogen substituents in the 2H-chromene moiety which were synthesized by a simple one-pot method. The molecular structure of the obtained compounds was confirmed by FT-IR, H and C NMR spectroscopy (including 2D methods), HRMS, elemental and single crystal X-ray analysis.

[On the problem of prevalence of psychotic disorders in adolescents].

Objective: To analyze indicators of the referral rate for highly specialized inpatient psychiatric care in adolescents with psychotic disorders.

Material And Methods: Clinical/dynamic and statistical methods were used to study the data of patients, aged 14-17 years, with psychotic mental disorders according to ICD-10, as well as the indicators of their hospitalization in psychiatric consulting and medical institution during the calendar year.

Results And Conclusion: The analysis of 2017 data shows that 6.

[The Impact of Effective Therapy With Atorvastatin on the Dynamics of Parameters of Electrical Instability in Patients with ST-Elevation Myocardial Infarction].

Aim: To assess the dynamics of parameters of myocardial electrical instability in patients with ST-elevation (STE) myocardial infarction (MI) treated with various doses of atorvastatin.

Materials And Methods: Patients with STEMI (n=70), who received atorvastatin 20 or 80 mg/day for 48 weeks, were divided into two groups: group "Е" - 38 patients (54.3 %) in whom by 48‑th week target values of low density lipoprotein cholesterol (LDLC) were achieved, and group "NE" - 32 patients (45.