Publications by authors named "Luke McLaughlin"
Background: HIV transmission during pregnancy and breastfeeding among serodiscordant heterosexual couples represents an ongoing barrier to the elimination of vertical transmission of HIV-1 infection in Canada.
Objective: To report a case of vertical HIV transmission during breastfeeding and examine the prevalence of risk factors for HIV transmission in the pregnancy and postpartum periods among serodiscordant couples where the male partner is HIV positive and female partner HIV negative.
Methods: Case report and retrospective chart review of HIV-serodiscordant pregnant couples over an eight-year period in Edmonton, Canada.
Article Synopsis
- The study investigates how genetic variations in angiotensin II pathway genes affect outcomes in septic shock patients.
- The research involved a genetic association study and in vitro experiments, focusing on patients in intensive care units.
- Results showed that a specific genetic variant (GG genotype of the angiotensin II type 1 receptor-associated protein) was linked to higher 28-day mortality and decreased mean arterial pressure in septic shock patients.