Impact of overweight and obesity on epicardial adipose tissue in children with type 1 diabetes.

Objectives: Epicardial adipose tissue (EAT) thickness, a novel marker of cardiovascular disease (CVD), is increased in children with a healthy weight and type 1 diabetes (T1D). The prevalence of obesity has increased in children with T1D and may confer additional CVD risk. The purpose of this study was to examine EAT thickness in youth with and without T1D in the setting of overweight/obesity.

Provider variability in the initial diagnosis and treatment of congenital hypothyroidism.

Background: Early diagnosis and expeditious treatment of newborns with congenital hypothyroidism (CH) is necessary to avoid mental retardation.

Methods: A survey of 44 practitioners in the southern US was conducted to better understand common practices regarding neonatal CH and the findings were compared with current guidelines in the US and Europe.

Results: Responses indicated some consensus that 10-15 μg of thyroid hormone/kg/day was the appropriate dosage.