Publications by authors named "Luke Carlson"

A cross-sectional survey was distributed to 1322 members of a 1-on-1 personalized strength training studio. A total of 366 respondents ( = 134 male and = 232 female), all aged over 20 years, reported considerable training experience, with 55% of the males and 42% of the females reporting 5+ years of experience. The data were analyzed and reported descriptively with differences >5% identified based on the use of a 5-point Likert scale, the sample size, and the nature of the observations.

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Article Synopsis
  • This study looks at how AI can help doctors understand the bones in the hip and knee better for surgeries, but also checks for problems like unfairness in these AI systems.
  • The focus is on using regular X-rays instead of fancy scans because X-rays are easier to get and cheaper.
  • They found ways to fix biases related to things like gender, race, and age, and shared their work to help doctors make better decisions and promote fairness in healthcare.
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Background: Osteosarcoma (OS) and chondrosarcoma (CS) are primary bone malignancies whose prognoses have stagnated despite advancements in surgical management, chemotherapy, radiation therapy, and immunotherapy. The role of the immune system in generating anti-cancer physiologic responses is critical to prognosis. Prior studies have explored if immune system activation via infection enhances survival in bone sarcomas without a clear consensus.

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Total joint arthroplasty (TJA) is the most common and fastest inpatient surgical procedure in the elderly, nationwide. Due to the increasing number of TJA patients and advancements in healthcare, there is a growing number of scientific articles being published in a daily basis. These articles offer important insights into TJA, covering aspects like diagnosis, prevention, treatment strategies, and epidemiological factors.

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To date no studies have compared resistance training loading strategies combined with dietary intervention for fat loss. Thus, we performed a randomised crossover design comparing four weeks of heavier- (HL; ~80% 1RM) and lighter-load (LL; ~60% 1RM) resistance training, combined with calorie restriction and dietary guidance, including resistance trained participants (n=130; males=49, females=81). Both conditions performed low-volume, (single set of 9 exercises, 2x/week) effort matched (to momentary failure), but non-work-matched protocols.

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Background: Virtual personal training might represent an uncomplicated, accessible, and time-efficient approach to supervised strength training, particularly under government-imposed lockdown or closure of fitness facilities. However, there appears a dearth of literature evaluating the efficacy of virtual personal training.

Methods: The present project considered two studies considering supervised virtual strength training.

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Background: Electronic health records (EHRs) are a rich source of longitudinal patient data. However, missing information due to clinical care that predated the implementation of EHR system(s) or care that occurred at different medical institutions impedes complete ascertainment of a patient's medical history.

Objective: This study aimed to investigate information discrepancies and to quantify information gaps by comparing the gynecological surgical history extracted from an EHR of a single institution by using natural language processing (NLP) techniques with the manually curated surgical history information through chart review of records from multiple independent regional health care institutions.

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PSD-95 () is an ionotropic glutamate receptor scaffolding protein essential in synapse stability and neurotransmission. PSD-95 levels are reduced during aging and in neurodegenerative diseases like Huntington's disease (HD), and it is believed to contribute to synaptic dysfunction and behavioral deficits. However, the mechanism responsible for PSD-95 dysregulation under these conditions is unknown.

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Budding Uninhibited By Benzimidazoles are a group of genes encoding proteins that play central roles in spindle checkpoint during mitosis. Improper mitosis may lead to aneuploidy which is found in many types of tumors. As a key mediator in mitosis, the dysregulated expression of BUBs has been proven to be highly associated with various malignancies, such as leukemia, gastric cancer, breast cancer, and liver cancer.

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Introduction: Understanding the impact of lockdown upon resistance training (RT), and how people adapted their RT behaviours, has implications for strategies to maintain engagement in similar positive health behaviours. Further, doing so will provide a baseline for investigation of the long-term effects of these public health measures upon behaviours and perceptions, and facilitate future follow-up study.

Objectives: To determine how the onset of coronavirus (COVID-19), and associated 'lockdown', affected RT behaviours, in addition to motivation, perceived effectiveness, enjoyment, and intent to continue, in those who regularly performed RT prior to the pandemic.

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We are glad to introduce the first Journal Club of volume five, the first issue. This edition is focused on relevant studies published in the last years in the field of eccentric training, chosen by our editorial board members and their colleagues. We hope to stimulate your curiosity in this field and to share with you the passion for the sport, seen also from a scientific point of view.

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Background: Chronic pain affects more than 20% of adults in the United States and is associated with substantial physical, mental, and social burden. Clinical text contains rich information about chronic pain, but no systematic appraisal has been performed to assess the electronic health record (EHR) narratives for these patients. A formal content analysis of the unstructured EHR data can inform clinical practice and research in chronic pain.

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Article Synopsis
  • * A case study of EHR-based population studies revealed that while there is an increase in reporting good data practices and methodologies, many studies still lack essential standards such as data abstraction training and inter-observer agreement testing.
  • * To improve EHR-based clinical research, the study suggests the continuous development of frameworks, ontologies, and reporting guidelines to enhance data practices in this field.
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A key variable within resistance training (RT) is that of repetition duration: the time (seconds) taken to perform the concentric and eccentric muscle actions of a repetition. Research has produced equivocal results with regard to strength and muscle mass increases; many studies have created parity in the number of repetitions, but there has been disparity in the load used and the time under load (TUL). The purpose of this study was to compare load- and TUL-matched groups performing resistance exercise using different repetition durations.

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Objective: The aim of the study was to compare hyaluronate with triamcinolone injections in treating chronic low back pain suggestive of lumbar zygopophyseal joint arthropathy.

Design: This was a prospective, double-blind, randomized controlled trial. Thirty subjects were randomly assigned to receive bilateral L3-S1 lumbar zygopophyseal joint injections with triamcinolone (KA) or Synvisc-One (HA).

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Research has produced equivocal results with regard to eccentric (ECC) only compared with traditional concentric/eccentric resistance training (RT). When considered in relation to load- and repetition duration-accentuated (ECC) training as well as the use of isokinetic and isoinertial training methods, there is a relative dearth of literature considering multi-joint, multi-exercise RT interventions. The present study considered 59 male and female participants randomly divided in to 3 sex counterbalanced groups; ECC only (ECC, n = 20), repetition duration-accentuated ECC (ECC-A, n = 20), and traditional (CON, n = 19) performing full-body, effort matched RT programmes for 2 days·week for 10 weeks.

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Background: Understanding resistance exercise motives and participation is essential in increasing exercise adherence and reducing comorbidities. CrossFit is a fitness movement that has seen an explosive growth in popularity worldwide; however, little research has investigated the motivational factors within this "niche" resistance exercise environment. The aim of this study was to explore the motivational factors of CrossFit participants in comparison to other resistance exercise participants.

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Breakdown (BD) training has been advocated by multiple commercial and academic publications and authors, seemingly as a result of the acute hormonal and muscle activation responses it produces. However, there is a relative dearth of research that has empirically considered this advanced method of resistance training (RT) over a chronic intervention while appropriately controlling other RT variables. The present study considered 36 male and female participants divided into 3 groups: BD (n = 11), heavy-load breakdown (n = 14), and traditional (n = 11), performing full-body RT programs 2 times per week for 12 weeks.

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Pre-exhaustion (PreEx) training is advocated on the principle that immediately preceding a compound exercise with an isolation exercise can target stronger muscles to pre-exhaust them to obtain greater adaptations in strength and size. However, research considering PreEx training method is limited. The present study looked to examine the effects of a PreEx training programme.

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Purpose: To evaluate the radiation protective characteristics of a system designed to enhance operator protection while eliminating weight to the body and allowing freedom of motion.

Materials And Methods: Radiation doses to a mock interventionalist were measured with calibrated dosimeters in a clinical interventional suite. A standard lead apron (SLA; Pb equivalent, 0.

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