Publications by authors named "Luke Bridge"
Article Synopsis
- The study examines how the neutrophil-lymphocyte ratio (NLR) and lymphocyte-monocyte ratio (LMR) relate to outcomes in patients who suffered an acute ischaemic stroke and were treated with mechanical thrombectomy (MT).
- Researchers analyzed clinical and laboratory data from 121 patients, finding that a higher NLR and lower LMR at 24 hours post-MT were linked to worse functional outcomes assessed at 3 months.
- The study concludes that measuring NLR and LMR shortly after the stroke can help predict a patient's recovery status after three months, with specific cutoff values identified for these ratios.
Context: A number of authors have found that there exists a positive relationship between progression-free survival and overall survival in clinical trials of cancer treatments for particular types of metastatic cancer. However, such an outcome is consistent with an increase in progression-free survival generally leading to an increase, a decrease or no change in survival following disease progression (post-progression survival) and which of these theories is valid has yet to be thoroughly investigated.
Objective: To test theories of this nature in relation to the use of chemotherapy in treating four different types of metastatic cancer by performing a systematic search of published clinical trials.