Publications by authors named "Lukas Werner Prause"
Article Synopsis
- The study investigated the impact of statin use on prostate cancer (PCa) development and prostate-specific antigen (PSA) levels in a cohort of 4,314 men over nearly 10 years.
- Statin users (761 men) had significantly lower baseline and follow-up PSA levels compared to non-users, but the overall incidence of PCa was similar between the two groups, indicating statins did not reduce the risk of developing PCa.
- Additionally, statin users had a higher risk of overall mortality, suggesting that while they had lower PSA levels, statin use did not confer a protective effect against prostate cancer.
Objectives: To analyze the influence of aspirin (ASA) intake on PSA values and prostate cancer (PCa) development in a prospective screening study cohort.
Methods: 4314 men from the Swiss section of the European Randomized Study of Screening for Prostate Cancer (ERSPC) were included. A transrectal prostate biopsy was performed in men with a PSA level ≥ 3 ng/ml.