Publications by authors named "Lukas Mendes de Abreu"
Four Decades of Treatment for Actinic Cheilitis: Outcomes, Challenges, and the Introduction of a New Clinical Index.
Lukas Mendes de Abreu Talissa da Silva Medina Nívea Layani Mariah Juliani Cruz Izabel Regina Fisher Rubira Bullen Cássia Maria Fisher Rubira
J Stomatol Oral Maxillofac Surg
January 2025
Objective: To evaluate the clinical outcomes of surgical and non-surgical treatments for actinic cheilitis (AC) over a four-decade period and to introduce a novel Clinical Index for the Treatment and Control of Actinic Cheilitis (CITC-AC) for improved patient stratification and management.
Materials And Methods: A retrospective cohort study analyzed 151 patients diagnosed with AC treated at a university clinic between 1980 and 2020. Sociodemographic, clinical, and histopathological data were collected.
Article Synopsis
- The study aimed to create and validate a less invasive method for assessing oxidative stress markers in cells from the mouth.
- Exfoliated oral cells were collected from healthy individuals, using fluorescent probes to measure reactive oxygen species, mitochondrial membrane potential, and reduced glutathione, after exposing them to hydrogen peroxide to induce oxidative stress.
- Results indicated that cells under oxidative stress showed increased reactive oxygen species and decreased mitochondrial health and glutathione levels, suggesting the method can effectively assess oxidative stress and may help in evaluating oral diseases linked to this condition.