Publications by authors named "Lukas Leiner"
Article Synopsis
- Re-irradiation is common in precision oncology, but it's crucial to monitor previous doses to organs-at-risk (OAR) to prevent overdose, especially when using advanced techniques like SMART for targeting tumors near OAR.
- The study analyzed 18 patients with lung or liver tumors, comparing different dose accumulation methods by assessing cumulative doses in both the planning target volumes (PTV) and OAR across adaptive and theoretical treatments.
- Results showed significant dose increases to OAR, especially in the spinal cord, heart, and gastrointestinal areas during adaptive treatments, suggesting a risk of overdoses, while maintaining comparable PTV coverage compared to baseline plans.
