High-resolution nerve ultrasound and corneal confocal microscopy in taxane-induced polyneuropathy.

Background And Purpose: The role of high-resolution nerve ultrasound (HRUS) and corneal confocal microscopy (CCM) in the early detection of taxane-induced polyneuropathy (TIPN) is unclear. The present prospective longitudinal controlled observational pilot study estimates the role of HRUS and CCM in the early diagnosis of TIPN in breast cancer patients.

Methods: Fifteen breast cancer patients receiving paclitaxel and 15 healthy age matched controls were included.