Publications by authors named "Lukas Anschuetz"

Introduction: This study aims to improve the diagnostic yield of cervical fine-needle aspiration (FNA) through training on a novel liver model. Ultrasonography-guided fine-needle aspiration (US-FNA) is crucial for diagnosing head and neck lumps but requires meticulous execution. Limited resources often hinder systematic teaching, making practical models essential for training.

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  • * A study analyzed 156 patients, finding that the majority were male (62%), with a median age of 64 years. The most common types of cancer were squamous cell carcinoma, adenocarcinoma, and malignant melanoma.
  • * The results showed generally low morbidity post-surgery, but patients undergoing radiation therapy experienced more acute side effects like dermatitis and mucositis. Several factors, including cancer type and skull base involvement, negatively impacted overall and recurrence-free survival rates.
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  • This study focuses on improving cochlear implant procedures by testing a new robotic tool designed to minimize trauma during the insertion of electrodes, which is crucial for preserving hearing in patients with some remaining inner ear function.
  • Using a validated model, the researchers conducted 60 insertions (30 manual and 30 robot-assisted) and found that the robotic method significantly reduced force variation and intracochlear pressure peaks compared to manual techniques.
  • The findings suggest that robotic assistance allows for more controlled and consistent insertion speeds, potentially enhancing hearing preservation while indicating that further research is needed to address later stages of the surgery.
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Objective: To explore Chat Generative Pretrained Transformer's (ChatGPT's) capability to create multiple-choice questions about otorhinolaryngology (ORL).

Study Design: Experimental question generation and exam simulation.

Setting: Tertiary academic center.

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Purpose: There are challenges in understanding the biomechanics of the human middle ear, and established methods for studying this system show significant limitations. In this study, we evaluate a novel dynamic imaging technique based on synchrotron X-ray microtomography designed to assess the biomechanical properties of the human middle ear by comparing it to laser-Doppler vibrometry (LDV).

Methods: We examined three fresh-frozen temporal bones (TB) using dynamic synchrotron-based X-ray microtomography for 256 Hz and 512 Hz, stimulated at 110 dB and 120 dB SPL.

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The auditory ossicles amplify and transmit sound from the environment to the inner ear. The distribution of bone mineral density is crucial for the proper functioning of sound transmission as the ossicles are suspended in an air-filled chamber. However, little is known about the distribution of bone mineral density along the human ossicular chain and within individual ossicles.

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Purpose: The aim of this article was to systematically review the literature on the pediatric population surgically treated for cholesteatoma and describe the applied post-operative follow-up strategies.

Methods: A systematic review was conducted following the Primary Reporting Items for Systematic Review and Meta-analysis (PRISMA) statement recommendations. After running the selected search string in PubMed, Scopus and Google Scholar, studies in English, reporting on surgically treated pediatric cholesteatoma patients (age younger or equal to 18 year-old) were retrieved.

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Objective: Limitations in human kinematics during cochlear implantation induce pressure transients and increased forces on intracochlear structures. Herein, we present a novel head-mounted surgical tool designed for the motorized insertion of cochlear implant electrode arrays. The tool integrates a force measurement feature to overcome the lack of haptic feedback in current robotic solutions.

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Introduction: Rhino-orbital-cerebral mucormycosis (ROCM) is a rare angioinvasive fungal infection known to be associated with high morbidity and over 50% mortality. ROCM is becoming more common due to an increase in predisposing immunocompromising comorbidities as well as COVID-19.

Case Presentations: We report 2 cases - a 75-year-old woman with diabetes and a 39-year-old man with recurrent diabetic ketoacidosis.

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Objective: Evaluation at long term of the impact of the stereotactic surgery (SRS) on the vestibular function in vestibular schwannoma (VS) patients.

Study Design And Setting: Retrospective study in a tertiary referral center.

Patients: Fifty-one VS patients were included (34 females;17 males), aged from 41 to 78 years treated exclusively with SRS.

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  • * Endoscopic ear surgery offers enhanced visibility and precision for procedures like ossiculoplasty (OPL), crucial for correctly positioning prosthetics in the middle ear.
  • * The article aims to serve as a detailed surgical manual for various OPL techniques, using both autologous and synthetic materials, to aid in the practical application of these methods in clinical settings.
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The characterization of the vibrations of the middle ear ossicles during sound transmission is a focal point in clinical research. However, the small size of the structures, their micrometer-scale movement, and the deep-seated position of the middle ear within the temporal bone make these types of measurements extremely challenging. In this work, dynamic synchrotron-based X-ray phase-contrast microtomography is used on acoustically stimulated intact human ears, allowing for the three-dimensional visualization of entire human eardrums and ossicular chains in motion.

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Purpose: To compare the audiological outcomes, tympanic membrane (TM) healing rates and complication rates in patients undergoing endoscopic underlay and over-under tympanoplasty type I (TTI).

Methods: The study includes 95 patients who underwent endoscopic TTI in the period between 2018 and 2023: 56% of the patients had the underlay technique and 41% had the over-under technique. Data regarding pre- and postoperative hearing, perforation characteristics, surgical procedures, graft types and complications were retrospectively analyzed.

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Purpose: This study investigates the impact of the COVID-19 pandemic on complicated upper respiratory tract infections requiring surgical intervention in a tertiary referral center. The aim is to understand the consequences of pandemic-related measures and their subsequent relaxation on the incidence and characteristics of upper respiratory tract infection-related complications.

Methods: Patients who underwent surgery as a complication of upper respiratory tract infections between December 2014 to February 2023 were included.

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  • - This study compared two methods—auditory brainstem response (ABR) and extracochlear electrocochleography (ECochG)—to evaluate the effectiveness of floating mass transducer (FMT) placement in active middle ear implant (AMEI) surgery for patients with mixed hearing loss.
  • - 15 patients underwent AMEI implantation, and results showed that ABR successfully assessed coupling efficiency in all cases, whereas ECochG was effective in only eight, indicating that ABR is more reliable and robust.
  • - The research concluded that ABR provides more accurate predictions of coupling efficiency and is preferable for optimizing FMT placement during surgery, offering useful data for future clinical applications.
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Objective: Sialendoscopy is a minimally invasive diagnostic and therapeutic technique used in the treatment of various salivary gland diseases. To date, there are very few suitable training models other than the pig's head, which has been used at the European Sialendoscopy Training Center for 22 years. The goal of this study was to describe an ovine model for sialendoscopy training and compare the ovine model's to the human anatomy.

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Objective: The optimal strategy to treat loco-regionally advanced squamous cell carcinoma of the larynx (LSCC) remains to be defined. The goal of this single institution retrospective study was to report on oncologic outcome of advanced LSCC treated with curative intent.

Methods: Patients diagnosed and treated for stage T3-T4a LSCC between 2001 and 2014 were retrospectively analyzed.

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Objective: To correlate radiographic evidence of cholesteatoma in the retrotympanum with intraoperative endoscopic findings in cholesteatoma patients and to evaluate the clinical relevance of radiographic evidence of cholesteatoma in the retrotympanum.

Study Design: Case series with chart review.

Setting: Tertiary referral center.

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Background: To assess a large patient cohort with sinonasal malignancies focusing on regional involvement, recurrence and oncological outcome.

Methods: Patients (n = 144) with malignant tumors of the nasal cavity and paranasal sinuses were treated at our tertiary referral center between 2008 and 2019. A chart review on patient and tumor characteristics, treatment and long-term outcome was performed.

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Objective: To evaluate the feasibility of local anesthesia for Eustachian tube balloon dilation as an in-office procedure for the treatment of Eustachian tube dilatory dysfunction as a response to the restriction measures of the coronavirus disease 2019 pandemic.

Method: Patients with Eustachian tube dilatory dysfunction refractory to nasal steroids undergoing Eustachian tube balloon dilation in local anesthesia were enrolled in a prospective observational cohort between May 2020 and April 2022. The patients were assessed by using the Eustachian tube dysfunction questionnaire (ETDQ-7) score and Eustachian tube mucosal inflammation scale.

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Objectives: This study investigates the possible benefits and limitations of the digital image enhancement systems provided by Storz Professional Image Enhancement System (SPIES) during endoscopic ear surgery (EES) for cholesteatoma. An increased detection of cholesteatoma residuals during the final steps of endoscopic surgery using DIE technology was hypothesized.

Design: Cross-sectional study.

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Purpose: High-riding jugular bulbs (JBs) among other anatomical variations can limit surgical access during lateral skull base surgery or middle ear surgery and must be carefully assessed preoperatively. We reconstruct 3D surface models to evaluate recent JB classification systems and assess the variability in the JB and surrounding structures.

Methods: 3D surface models were reconstructed from 46 temporal bones from computed tomography scans.

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Nose surgery is challenging and needs a lot of training for safe and efficient treatments. Eye tracking can provide an objective assessment to measure residents' learning curve. The aim of the current study was to assess residents' fixation duration and other dependent variables over the course of a dedicated training in functional endoscopic sinus surgery (FESS).

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