Publications by authors named "Luka Hoeben"
Atherosclerosis
October 2024
Article Synopsis
- Tobacco smoking increases the risk of atherosclerotic disease, particularly in women, leading researchers to investigate how gene expression in plaques differs between smokers and non-smokers based on sex.
- Analyzing gene expression in 625 carotid plaques revealed that the CRLF1 gene was significantly upregulated in smokers, especially in females, indicating a sex-specific response to smoking.
- The findings suggest that CRLF1, linked to smooth muscle cells and extracellular matrix, may contribute to the heightened cardiovascular risk in female smokers compared to their male counterparts.
