Publications by authors named "Luiza S Nader"
Article Synopsis
- Antibody-mediated rejection is a growing concern in liver transplantation, specifically regarding donor-specific antibodies (DSAs) and their effects on graft survival, with a lack of research on pediatric populations.
- A study involving 67 pediatric liver transplant recipients identified that 28.3% had pre-transplant DSAs, while 48.4% developed them post-transplant, and rejection episodes were confirmed in 13 patients.
- The presence of post-transplant DSAs significantly increased the risk of rejection, underscoring the need to include DSA monitoring in the care of pediatric liver transplant patients.
Article Synopsis
- Hepatic artery complications (HACs) after pediatric liver transplantation can lead to significant health issues, and this study aims to understand how common they are, how they are managed, and what outcomes arise from these complications.
- The research utilizes the international HEPATIC Registry, collecting data on pediatric patients under 18 who experienced HAC within the last 20 years, focusing on survival rates and treatment success.
- Ethical approval will be obtained from all participating sites, and findings will be shared at conferences and in academic journals, with the study registered on ClinicalTrials.gov (NCT05818644).
Introduction: Eosinophilic esophagitis is a newly recognized entity, in which there is significant evidence available that clearly demonstrates the positive impact of PPIs on reducing esophageal eosinophilia in individuals across different age groups, including children, adolescents, and adults. Multiple mechanisms have been proposed to explain how this treatment effect occurs. In Brazil, there seems to be a lack of studies that have prospectively assessed the clinical and therapeutic response rate in pediatric patients with EoE.
View Article and Find Full Text PDFPrevalence, management and efficacy of treatment in portal vein obstruction after paediatric liver transplantation: protocol of the retrospective international multicentre PORTAL registry.
Bader A Alfares Hubert P J van der Doef Barbara E Wildhaber Thomas Casswall Greg Nowak Luiza S Nader
BMJ Open
July 2023
Article Synopsis
- - The study investigates portal vein obstruction (PVO) in pediatric liver transplant patients, focusing on its prevalence, treatment practices, and outcomes through a global collaboration of 25 medical centers.
- - It utilizes a registry to gather data from patients diagnosed with PVO between 2001 and 2021, aiming to measure factors like treatment success and complications following interventions.
- - Approved by an ethics board, the study plans to share findings in academic journals and conferences, contributing to the understanding of PVO management post-liver transplantation.