Publications by authors named "Luiza Aparecida Luna Silverio"
Although preliminary evidence suggests 's efficacy in symptom control for anxiety and depression-psychiatric disorders that significantly impact mental health-much remains to be understood about its effects on the central nervous system (CNS) and how to optimize treatment for these disorders. This study aims to conduct a narrative review to evaluate pharmaceutical care in treating symptoms of anxiety and depression alongside use, focusing on safety and therapeutic efficacy optimization. We seek to conceptualize anxiety and depression disorders, review evidence on use, evaluate the evidence quality, and identify knowledge gaps.
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- Cannabidiol, a compound derived from the Cannabis plant, has promising pharmacological effects, particularly when used topically, and is linked to fewer adverse events compared to other cannabinoids.
- The study conducts a scoping review to analyze the efficacy of topical cannabidiol through in vivo models, guided by the Joanna Briggs Institute's methodology and established inclusion criteria.
- Though further research is required to determine optimal dosages, cannabidiol shows potential in treating various health issues, including glaucoma, atopic dermatitis, epidermolysis bullosa, and pyoderma gangrenosum.
A poloxamer 407 (P407)-Casein hydrogel was chosen to carry polycaprolactone nanoparticles carrying terbinafine (PCL-TBH-NP). In this study, terbinafine hydrochloride (TBH) was encapsulated into polycaprolactone (PCL) nanoparticles, which were further incorporated into a poloxamer-casein hydrogel in a different addition order to evaluate the effect of gel formation. Nanoparticles were prepared by the nanoprecipitation technique and characterized by evaluating their physicochemical characteristics and morphology.
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- Many plants have traditional uses for treating diseases, but often lack scientific backing for their safety and effectiveness.
- The review focuses on a specific plant genus, highlighting its pharmacological activities and potential uses of its often-discarded parts (like leaves, bark, and seeds).
- This genus shows promising properties such as antioxidant, anti-inflammatory, and antiviral effects, yet few products are currently available that utilize it as an active ingredient.