Publications by authors named "Luiz R Grassmann Bechara"
Article Synopsis
- Exercise positively impacts health and helps diagnose aging-related diseases by altering mitochondrial function in muscles.
- The study found that a single exercise session triggers a cycle of mitochondrial fragmentation followed by fusion, which helps delay the decline of physical fitness with aging.
- AMPK plays a critical role in maintaining physical fitness and enhancing muscle function through the regulation of mitochondrial dynamics, suggesting that targeting mitochondrial processes and AMPK could improve muscle function in older adults.
Objective:: We aimed to determine whether aerobic training decreases superoxide levels, increases nitric oxide levels, and improves endothelium-dependent vasodilation in the aortas of spontaneously hypertensive rats.
Methods:: Spontaneously hypertensive rats (SHR) and Wistar Kyoto rats (WKY) were distributed into 2 groups: sedentary (SHRsd and WKYsd, n=10 each) and swimming-trained (SHRtr, n=10 and WKYtr, n=10, respectively). The trained group participated in training sessions 5 days/week for 1 h/day with an additional work load of 4% of the animal's body weight.