Publications by authors named "Luiz Lisboa"

Three-dimensional (3D) printing is a new method of creating anatomical models, which can enhance the training of students and health professionals. The large breed-variation in dogs means that interpretation of thoracic radiographs can be challenging for the inexperienced radiologist. The aim of this study was to develop digital and printed 3D cardiac models from six canine breeds and evaluate their use as a tool for studying breed variations in radiology.

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Article Synopsis
  • The study compares the outcomes of patients with acute myocardial infarction (AMI) undergoing coronary artery bypass grafting (CABG) using either a single arterial graft (SAG) or multiple arterial grafts (MAGs).
  • Conducted with 4,053 patients, the research focused on 238 individuals who had CABG within one week of AMI diagnosis, resulting in a comparison of 70 patients after matching based on clinical characteristics.
  • Findings indicate that while surgery duration was longer for the MAG group, there were no significant differences in clinical outcomes, readmissions, or complications between MAG and SAG groups within 30 days and up to five years post-surgery.
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Background: The analysis of indicators such as hospital readmission rates is crucial for improving the quality of services and management of hospital processes.

Objectives: To identify the variables correlated with hospital readmission up to 30 days following coronary artery bypass grafting (CABG).

Methods: Cross-sectional cohort study by REPLICCAR II database (N=3,392) from June 2017 to June 2019.

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Background: Analyses of extensive registries indicate adverse outcomes for women undergoing coronary artery bypass grafting (CABG) surgery, while randomized studies often lack representativeness.

Objective: To compare adjusted hospital outcomes between men and women undergoing CABG.

Methods: From July 2017 to June 2019, 3991 patients underwent primary isolated CABG, both electively and urgently, in 5 hospitals in the state of São Paulo, Brazil.

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Background: Identifying risk factors in cardiovascular surgery assists in predictability, resulting in optimization of outcomes and cost reduction.

Objective: This study aimed to identify preoperative and intraoperative risk predictors for prolonged hospitalization after coronary artery bypass grafting (CABG) surgery in the state of São Paulo, Brazil.

Methods: A cross-sectional analysis using data from the REPLICCAR II database, a prospective, consecutive, multicenter registry that included CABG surgeries performed between August 2017 and July 2019.

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Introduction: Along with cardiopulmonary bypass time, aortic cross-clamping time is directly related to the risk of complications after heart surgery. The influence of the time difference between cardiopulmonary bypass and cross-clamping times (TDC-C) remains poorly understood.

Objective: To assess the impact of cardiopulmonary bypass time in relation to cross-clamping time on immediate results after coronary artery bypass grafting in the Registro Paulista de Cirurgia Cardiovascular (REPLICCAR) II.

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Objectives: The aim of this analysis was to compare the effect of extubating in the operating room (OR) versus and the intensive care unit (ICU) among patients undergoing coronary artery bypass grafting (CABG).

Design: A retrospective cohort analysis.

Setting: Ten cardiac referral hospitals in Latin America; participants of the São Paulo Registry of Cardiovascular Surgery II (REPLICCAR II).

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Background: The short-term results after using arterial grafts still raise questions and doubts for medical society.

Objective: To compare the immediate outcomes of patients undergoing single arterial graft versus multiple arterial grafts coronary artery bypass grafting surgery.

Methods: Cross-sectional cohort study in the São Paulo Registry of Cardiovascular Surgery II (REPLICCAR II).

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Objective: The objective of this study is to evaluate protamine sulfate effects on graft's blood flow by comparing transit-time flow measurement (TTFM) values before and after protamine administration.

Methods: This is an observational study with data collected between years 2018 and 2020. Immediate graft patency was evaluated using TTFM.

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Clinical prediction models for deep sternal wound infections (DSWI) after coronary artery bypass graft (CABG) surgery exist, although they have a poor impact in external validation studies. We developed and validated a new predictive model for 30-day DSWI after CABG (REPINF) and compared it with the Society of Thoracic Surgeons model (STS). The REPINF model was created through a multicenter cohort of adults undergoing CABG surgery (REPLICCAR II Study) database, using least absolute shrinkage and selection operator (LASSO) logistic regression, internally and externally validated comparing discrimination, calibration in-the-large (CL), net reclassification improvement (NRI) and integrated discrimination improvement (IDI), trained between the new model and the STS PredDeep, a validated model for DSWI after cardiac surgery.

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Objective: To evaluate the impact of adherence to the cardiac surgical checklist on mortality at the teaching hospital.

Methods: A retrospective cohort study after the implementation of the cardiac surgical safety checklist in a reference hospital in Latin America. All patients undergoing coronary artery bypass surgery and/or heart valve surgery from 2013 to 2019 were analyzed.

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The pathobiology of in non-cystic fibrosis bronchiectasis (nCFB) is poorly defined. When present at high density or "inoculum," some methicillin-sensitive (MSSA) can inefficiently degrade antistaphylococcal β-lactam antibiotics via BlaZ penicillinases (termed the "inoculum effect" [IE]). Given the high burden of organisms in bronchiectatic airways, this is particularly relevant.

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pulmonary infection was incidentally diagnosed in an asymptomatic patient suspected to have metastatic osteosarcoma. Molecular diagnosis was imperative to fungal identification given overlapping histopathological features with histoplasmosis. This report documents a case of isolated pulmonary emergomycosis in an otherwise immunocompetent patient while discussing diagnostic and management pitfalls of this emerging and underdiagnosed infection.

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Background: The performance of traditional scores is significantly limited to predict mortality in high-risk cardiac surgery. The aim of this study was to compare the performance of STS, ESII and HiriSCORE models in predicting mortality in high-risk patients undergoing CABG.

Methods: Cross-sectional analysis in the international prospective database of high-risk patients: HiriSCORE project.

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Background And Aim Of The Study: This study analyzed the arrival of coronavirus disease 2019 (COVID-19) in Brazil and its impact on coronary artery bypass grafting (CABG) surgery.

Methods: Patients undergoing isolated CABG in six hospitals in Brazil were divided into two periods: pre-COVID-19 (March-May 2019, N = 468) and COVID-19 era (March-May 2020, N = 182). Perioperative data were included on a dedicated REDCap platform.

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Article Synopsis
  • - Ventricular septal rupture (VSR) is a critical but common complication following acute coronary syndrome, with high mortality rates, and there has been a noticeable increase in such cases during and after the COVID-19 quarantine period.
  • - A study analyzing data from 2004 to 2020 found 33 acute VSR cases where 45.8% of those who underwent surgery died within 30 days, with diabetes, age, cardiogenic shock, and certain medical interventions linked to higher mortality.
  • - The research indicates a rise in VSR cases during 2020 compared to previous years, suggesting that fewer patients sought necessary medical treatment during the pandemic, contributing to the increased incidence and ongoing high mortality rates in
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Background: Dual antiplatelet therapy is recommended for patients with acute coronary syndromes (ACS). Approximately 10% to 15% of these patients will undergo coronary artery bypass graft (CABG) surgery for index events, and current guidelines recommend stopping clopidogrel at least 5 days before CABG. This waiting time has clinical and economic implications.

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Introduction: The presence of mild to moderate pericardial effusion after cardiac surgery is common and oral medical therapy is usually able to treat it. Larger effusions are less frequent and surgical intervention is usually necessary. However, there are some rare cases of large effusions that are recurrent even after intervention and become challenging to treat.

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It is observed that death rates in cardiac surgery has decreased, however, root causes that behave like triggers of potentially avoidable deaths (AD), especially in low-risk patients (less bias) are often unknown and underexplored, Phase of Care Mortality Analysis (POCMA) can be a valuable tool to identify seminal events (SE), providing valuable information where it is possible to make improvements in the quality and safety of future procedures. Our results show that in São Paul State, only one third of AD in low-risk cardiac surgery was related to specific surgical problems. After a revisited analysis, 75% of deaths could have been avoided, which in the pre-operative phase, the SE was related judgment, patient evaluation and preparation.

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Introduction: Anemia and blood transfusion are risk factors for morbidity/mortality in patients undergoing cardiac surgery with cardiopulmonary bypass (CPB). The objective of this study is to analyze the association of blood transfusion with morbidity/ mortality in patients undergoing coronary artery bypass grafting (CABG) under CPB in the state of São Paulo, Brazil.

Methods: This is a retrospective analysis using the State of São Paulo Registry of Cardiovascular Surgery from November 2013 to August 2014.

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Since the beginning of the coronavirus disease (COVID-19) pandemic, in March 2020, the number of people infected with COVID-19 worldwide increases continuously. Brazil is being followed with great concern in the international media, as it can, very soon, be the epicenter of the pandemic. Initial surgical data suggest that patients who acquire COVID-19 in the perioperative period are prone to a higher morbidity and mortality, however, evidence in cardiac surgery is still scarce.

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