Phytochemical Analysis and Antinociceptive Properties of Hydroalcoholic Extracts of Aleurites moluccanus Bark.

is used in folk medicine to treat many diseases including pain and inflammatory processes in general. Considering the potential of the leaf extract, evidenced in a previous study, the present study investigates the antinociceptive and anti-inflammatory properties of the hydroethanolic extract of bark and isolated compounds in animal models of pain. The antinociceptive and anti-inflammatory activities of bark were evaluated through hyperalgesia induced by carrageenan, PGE, cytokines, bradykinin, epinephrine, Freund's complete adjuvant, and lipopolysaccharide.