Publications by authors named "Luiz Felipe Ribeiro Pinto"
Analysis of mutations in TP53, APC, K-ras, and DCC genes in the non-dysplastic mucosa of patients with inflammatory bowel disease.
Davy Carlos Mendes Rapozo Ana Braunstein Grinmann Ana Teresa Pugas Carvalho Heitor Siffert P de Souza Sheila Coelho Soares-Lima Luiz Felipe Ribeiro Pinto
Int J Colorectal Dis
October 2009
Background And Aims: Patients with ulcerative colitis (UC) and Crohn's disease (CD) have a high risk for colorectal cancer (CRC). To understand the molecular basis of colitis-associated CRC, we analyzed alterations in TP53, APC, K-ras, and DCC genes in the non-dysplastic UC and CD colon.
Materials And Methods: Endoscopic biopsies were collected from six predefined colon sites of 35 UC and 12 CD patients for DNA extraction and genetic analysis.