Porcine peritoneum as source of biocompatible collagen in mice.

Purpose: To investigate the biocompatibility and biodegradability of a membrane made from porcine peritoneum.

Methods: The membrane (5x5 mm) was inserted in the subcutaneous tissue on the back of 15 mice, which were killed after 1, 3 and 9 weeks (ISO 10993-6). The cellular components of the inflammatory response and degradation of the membrane were analyzed in hematoxylin-eosin-stained histological sections.