Excessive occlusal load on chemically modified and moderately rough titanium implants restored with cantilever reconstructions. An experimental study in dogs.

Objective: To evaluate the outcomes of excessively loaded implants.

Material And Methods: In five dogs, all mandibular premolars were extracted. After 3 months, six implants (three SLA® and three SLActive®) were placed (S).

Support Vector Data Descriptions and $k$ -Means Clustering: One Class?

We present ClusterSVDD, a methodology that unifies support vector data descriptions (SVDDs) and $k$ -means clustering into a single formulation. This allows both methods to benefit from one another, i.e.

Transductive Regression for Data With Latent Dependence Structure.

Analyzing data with latent spatial and/or temporal structure is a challenge for machine learning. In this paper, we propose a novel nonlinear model for studying data with latent dependence structure. It successfully combines the concepts of Markov random fields, transductive learning, and regression, making heavy use of the notion of joint feature maps.

Synthetic Parathyroid Hormone May Augment Bone Volume in Autogenous Grafts: A Study in Rats.

Background: Synthetic parathyroid hormone [PTH(1-34)] has been investigated for its benefits on bone healing and osteoporosis treatment; however, there is little information regarding bone grafts. This study therefore investigates the effect of PTH(1-34) on autogenous bone graft healing.

Methods: Bone grafts were harvested from the calvarium of rats with a trephine bur (3-mm internal diameter) and placed on the cortex near the mandible angle with a titanium screw.

Dynamics of soft tissue healing at implants and teeth: a study in a dog model.

Objective: The aim of this study was to describe and to compare some characteristics of the soft tissue healing process around teeth and implants after flap surgery.

Material And Methods: Five adult beagle dogs had their third and fourth lower premolars extracted. After 3 months, four implants per dog were placed on the healed alveolar ridge and allowed to heal non-submerged during 3 months.

Role of rhBMP-2 and rhBMP-7 in the metabolism and differentiation of osteoblast-like cells cultured on chemically modified titanium surfaces.

This study analyzed the role of recombinant human bone morphogenetic protein 2 (rhBMP-2) and recombinant human bone morphogenetic protein 7 (rhBMP-7) in the adhesion and differentiation of rat osteoblast-like (osteo-1) cells cultured on chemically modified titanium surfaces. Osteo-1 cells were cultured on chemically modified (modified sandblasted and acid-etched) titanium surfaces in 3 different types of medium: control, medium supplemented with 20 ng/mL rhBMP-2, and medium supplemented with 20 ng/mL rhBMP-7. The following parameters were evaluated: cell adhesion after 24 hours; total protein content; collagen content and alkaline phosphatase (AP) activity after 7, 14, and 21 days; and calcified nodule formation after 21 days.

Two-year randomized clinical trial of enamel matrix derivative treated infrabony defects: radiographic analysis.

Background: This split-mouth, double-blind randomized controlled trial evaluated radiographic changes in infrabony defects treated with open flap debridement (OFD) or OFD associated with enamel matrix derivative (EMD) after a 24-month follow-up. The radiographic distance from the CEJ to the bottom of the defect (BD) was considered the primary outcome. CEJ-BC and defect angle were secondary outcomes.

Richness, composition and trophic groups of an avian community in the Pernambuco Endemism Centre, Alagoas, Brazil.

In northeastern Brazil, the reduction of the natural forest cover to a series of small, isolated fragments has had negative consequences for the local avian fauna, in particular, a loss of the more specialized species, while the populations of some generalists have tended to increase. The present study focuses on the composition and trophic groups of a bird community on a farm in the northeastern Brazilian state of Alagoas. Monthly surveys were conducted between November 2008 and October 2009, based on mist-netting and systematic observations.

Effect of Center-Pivot Irrigation in the Rust and Brown Eye Spot of Coffee.

Incidence of rust (caused by Hemileia vastatrix) and brown eye spot (caused by Cercospora coffeicola) of coffee was evaluated for 2 years in southern Minas Gerais, Brazil, in a center-pivot-irrigated coffee crop with different water application levels. Treatments consisted of six water levels of 0 (nonirrigated), 60, 80, 100, 120, and 140% applied according to class A evaporation pan (CAE). Progress of disease was influenced significantly by different water levels; the highest incidence of rust occurred with lower water levels-0 (nonirrigated), 60, and 80% CAE-whereas the lowest incidence was detected with larger water levels: 120 and 140% CAE.

Ultrastructural and immunohistochemical study of early repair of alveolar sockets after the extraction of molars from alendronate-treated rats.

The aim of the present research was to analyze ultrastructural and immunohistochemical aspects of the alveolar repair after the extraction of molars of alendronate (ALN)-treated rats. Wistar rats received 2.5mg/kg body wt/day of ALN during 14 days previously and 7, 14 and 21 days after the extraction of the second mandibular molar.

Aqueous extract of pecan nut shell (Carya illinoensis [Wangenh.] K. Koch) exerts protection against oxidative damage induced by cyclophosphamide in rat testis.

This study investigated the protective effect of pecan nut (Carya illinoensis) shell aqueous extract (AE) on the oxidative and morphological status of rat testis treated with cyclophosphamide (CP). Wistar rats received water or AE (5%) ad libitum for 37 days. On day 30, half of each group received a single intraperitoneal administration of vehicle or CP 200 mg/kg.

Immunolocalization of bone morphogenetic protein 2 during the early healing events after guided bone regeneration.

Objective: The objective of this study was to evaluate the immunolocalization of bone morphogenetic protein 2 (BMP-2) after autogenous block grafting covered or not with an e-PTFE membrane.

Study Design: Forty-eight rats were divided into 2 groups, autogenous block graft (B) and autogenous block graft + e-PTFE membrane (MB), and were evaluated by immunohistochemistry at baseline and 3, 7, 14, 21, and 45 days.

Results: The largest number of positive cells in the recipient bed was observed after 3 days in both groups.

Surgical experience influences 2-stage implant osseointegration.

Purpose: With the increasing number of surgical procedures for osseointegrated implant placement, there has also been an increase in the number of professionals performing this procedure. Surgeons undergo different types of training, and this may influence their surgical experience. The objective of this study was to evaluate the effect of surgical experience on the osseointegration of dental implants.

Relationship between herpesviruses and periodontopathogens in patients with HIV and periodontitis.

Background: The purpose of the present study is to verify a possible association between herpesviruses and periodontal pathogens in individuals with human immunodeficiency virus (HIV) and periodontitis.

Methods: Twenty-seven patients with HIV and chronic periodontitis and 23 patients with HIV and gingivitis were included in the study. Probing depth, clinical attachment loss, gingival index, and plaque index were recorded.

Subgingival ultrasonic instrumentation of residual pockets irrigated with essential oils: a randomized controlled trial.

Aim: To evaluate the clinical efficacy of subgingival ultrasonic instrumentation irrigated with essential oils (EOs) of residual periodontal pockets.

Material And Methods: Sixty-four individuals with chronic periodontitis were invited to participate in this randomized, double-blind, parallel, and placebo-controlled clinical trial. All subjects received non-surgical periodontal therapy.

Predictors of tooth loss during long-term periodontal maintenance: a systematic review of observational studies.

Objective: To systematically assess the factors influencing tooth loss during long-term periodontal maintenance (PM).

Methods: CENTRAL, MEDLINE and EMBASE were searched up to and including September 2009. Studies limited to patients with periodontitis who underwent periodontal therapy and followed a maintenance care programme for the at least 5 years were eligible for inclusion in this review.

Effects of occlusal overload on peri-implant tissue health: a systematic review of animal-model studies.

Background: This study systematically evaluates the effect of occlusal overload (OV) on peri-implant tissue health in animal studies.

Methods: MEDLINE, EMBASE, and LILACS databases were searched for articles published up to and including January 2010. Studies that reported outcomes of non-splinted titanium dental implants submitted to OV were eligible for inclusion.

Early antimicrobial activity of intracanal medications on the external root surface of periodontally compromised teeth.

Objective: To verify the effect of scaling and root planing on the antimicrobial activity of intracanal medications on the external root surface of periodontally compromised teeth.

Method And Materials: Forty single-rooted extracted teeth were randomly assigned for visible calculus removal or scaling and root planing. Samples were separated into four groups-chlorhexidine, tetracycline hydrochloride, calcium hydroxide, or saline solution-and immersed in semisolid media and seeded with Micrococcus luteus for 24 hours.

Assessment of the availability of bone volume for grafting in the donor retromolar region using computed tomography: a pilot study.

Purpose: The purpose of this study was to evaluate the area and volume of bone available for grafting in a donor retromolar region using computed tomography (CT).

Materials And Methods: Ten patients previously scanned by multislice CT were selected for evaluation. Images from partially and completely dentate patients at least 18 years of age were included in the study; those from patients with impacted or erupted third molars or intrabony lesions in the study area were not included.

Root-coverage procedures for the treatment of localized recession-type defects: a Cochrane systematic review.

Background: The purpose of this review is to evaluate the effectiveness of different root-coverage procedures in the treatment of recession-type defects.

Methods: The Cochrane Oral Health Group Trials Register, Cochrane Central Register of Controlled Trials, MEDLINE, and EMBASE were searched for entries up to October 2008. There were no restrictions regarding publication status or the language of publication.

Treatment of infrabony defects with or without enamel matrix proteins: a 24-month follow-up randomized pilot study.

Objective: To evaluate a comparison of open-flap debridement (OFD) with or without the use of enamel matrix proteins (EMP) for the treatment of infrabony defects.

Method And Materials: Ten volunteers (38 infrabony defects) were randomized to receive OFD+EMP (test site) and OFD (control site). Clinical outcomes included mean changes in Plaque Index, Gingival Index, probing pocket depth (PPD), relative attachment level (RAL), gingival recession, width of keratinized tissue, and dental mobility at baseline and at 24 months.

Influence of osteopenia in autogenous bone graft healing with or without expanded polytetrafluoroethylene membranes: histologic and histomorphometric study in rats.

Purpose: The aim of this study was to quantitatively evaluate and qualitatively describe autogenous bone graft healing with or without an expanded polytetrafluoroethylene (e-PTFE) membrane in ovariectomized rats.

Materials And Methods: Eighty Wistar rats, weighing approximately 300 g each, were used. A graft was obtained from the parietal bone and fixed to the sidewall of each animal's left mandibular ramus.

Root coverage procedures for the treatment of localised recession-type defects.

Background: Gingival recession is defined as the oral exposure of the root surface due to a displacement of the gingival margin apical to the cemento-enamel junction and it is regularly linked to the deterioration of dental aesthetics. Successful treatment of recession-type defects is based on the use of predictable periodontal plastic surgery (PPS) procedures.

Objectives: To evaluate the effectiveness of different root coverage procedures in the treatment of recession-type defects.

Systematic review of periodontal plastic surgery in the treatment of multiple recession-type defects.

Objectives: The objectives of this systematic review were (1) to evaluate results obtained with different periodontal plastic surgery procedures in the treatment of multiple recession-type defects and (2) to assess differences in results from randomized controlled trials and other types of studies (i.e., controlled clinical trials and case series).

The influence of tobacco smoking on the outcomes achieved by root-coverage procedures: a systematic review.

Background: The authors conducted a systematic review to evaluate the effect of smoking on the clinical outcomes achieved by periodontal plastic surgery procedures in the treatment of recession-type defects.

Types Of Studies Reviewed: The authors performed an electronic search on MEDLINE, EMBASE and the Cochrane Central Register of Controlled Trials (CENTRAL) for randomized controlled clinical trials, controlled clinical trials and case series that involved at least six months' follow-up. They looked for studies published through June 2008 that compared the outcome measures achieved by smokers and nonsmokers after they underwent periodontal plastic surgery procedures for treatment of gingival recession.