Safety and clinical effectiveness of a compounded sustained-release formulation of buprenorphine for postoperative analgesia in New Zealand White rabbits.

Objective: To determine the clinical effectiveness and safety of a compounded sustained-release formulation of buprenorphine, compared with effects of regular buprenorphine, for postoperative analgesia in rabbits.

Design: Blinded randomized controlled clinical trial.

Animals: 24 purpose-bred adult male New Zealand White rabbits.