Publications by authors named "Luise Zimmermann"
Article Synopsis
- A study analyzed the use of rituximab in patients with autoimmune encephalitis (AE), particularly focusing on those with NMDA receptor (NMDAR) and other related conditions, to see how it correlates with long-term outcomes.
- Out of 358 patients, 163 received rituximab, with treatment starting significantly earlier for NMDAR and LGI1-AE, showing improved functional outcomes and reducing relapse rates compared to those who didn't receive the drug.
- The findings suggest that early initiation of rituximab therapy is potentially effective and safe for treating several types of AE, highlighting its benefits especially for NMDAR and LGI1 cases.
Heat shock proteins (HSPs) are molecular chaperones that play a pivotal role in correct folding, stabilization and intracellular transport of many client proteins including those involved in oncogenesis. HSP70, which is frequently overexpressed in prostate cancer (PCa), has been shown to critically contribute to tumor cell survival, and might therefore represent a potential therapeutic target. We treated both the androgen receptor (AR)-positive LNCaP and the AR-negative PC-3 cell lines with the pharmacologic HSP70 inhibitor VER155008.
View Article and Find Full Text PDFRecent evidence suggests that infants as young as 12 month of age use pointing to communicate about absent entities. The tacit assumption underlying these studies is that infants do so based on tracking what their interlocutor experienced in a previous shared interaction. The present study addresses this assumption empirically.
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