Publications by authors named "Luise Victoria ClaaSS"
Influence of noninvasive brain stimulation on connectivity and local activation: a combined tDCS and fMRI study.
Eur Arch Psychiatry Clin Neurosci
June 2024
Article Synopsis
- The study investigates the impact of transcranial direct current stimulation (tDCS) on executive function and resting-state connectivity in the brain, focusing on the left dorsolateral prefrontal cortex (DLPFC).
- Researchers used a double-blind design with 36 healthy participants, comparing anodal, cathodal, and sham stimulation while measuring brain activity via fMRI during and after stimulation.
- Results showed significant changes in resting-state connectivity but no effects on task-related brain activation or working memory performance, and the findings did not align with previous studies, raising questions about methodology for future research.
Purpose: SARS-CoV-2 vaccines cause acute ipsilateral lymph node swelling in an important proportion of vaccines. Thus far, no malignant lymphadenopathies have been reported in temporal context to vaccination in the ipsilateral draining lymph node areas.
Experimental Design: Prompted by two cases with unilateral axillary lymphomas that occurred ipsilaterally to prior SARS-CoV-2 vaccination, we systematically retrieved all B-cell non-Hodgkin lymphomas at two German University Medical Centers diagnosed before and after introduction of SARS-CoV-2 vaccines in Germany.
The two most common antibody targeting principles in oncology are the induction of direct antitumor effects and the release of antitumor T cell immunity by immune checkpoint blockade. These two principles, however, may be overlapping if the targeted checkpoint molecule is not located on the immune cell but on the tumor cell itself. Secondary resistance by epitope escape may therefore remain a challenge in both settings.
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