Null Effect of Olfactory Training With Patients Suffering From Depressive Disorders-An Exploratory Randomized Controlled Clinical Trial.

Unlabelled: Due to a close functional relation between brain areas processing emotion and those processing olfaction, major depression is often accompanied by reduced olfactory function. Such hyposmia can be improved by regular olfactory training (OT) over several months. As this training furthermore improves subjective well-being, we explored whether OT is a useful complementary strategy for depression treatment.

The impact of severity, course and duration of depression on olfactory function.

Background: People with diagnosed depression often express a reduced olfactory capacity, although previous studies exhibited mixed results. However, research focused mainly on psychiatric inpatients and potential influence variables were rarely considered. We therefore examined the influence of severity, course and duration of depression on olfactory function.