Publications by authors named "Luise Bergmann"
Article Synopsis
- The study analyzed the proteomic profiles of 79 bladder cancer samples, categorizing them into non-muscle-invasive (NMIBC), muscle-invasive (MIBC), and neoadjuvant-treated MIBC groups.
- MIBC showed significant changes in the extracellular matrix and immune response-related proteins, as well as a decrease in proteins related to cell adhesion and lipid metabolism compared to NMIBC.
- The research identified multiple proteomic subgroups within MIBC and NMIBC that correlate with tissue type and metabolic pathways, revealing complex tumor-stroma interactions and significant genomic alterations in the cancers.
Background: Intrahepatic cholangiocarcinoma (ICC) represents an aggressive carcinoma with a dismal prognosis. For resection specimens, histopathological prognosticators are limited to standard AJCC parameters. Tumor budding (TB), a quantitative leviable parameter for tumor cell separation and infiltration is a promising prognostic factor for several cancers.
View Article and Find Full Text PDF