Publications by authors named "Luisa Van den Bosch"
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Synopsis of recent research by authors named "Luisa Van den Bosch"
Luisa Van Den Bosch's research primarily focuses on the structural biology and functional mechanisms of bacterial surface polysaccharides and their roles in microbial virulence, particularly in Shigella flexneri.
Her studies highlight the importance of O-antigen chain length regulation by proteins like Wzz in influencing bacterial motility and virulence, uncovering structural similarities among polysaccharide co-polymerases that affect chain length distributions.
Recent findings suggest that mutations in bacterial lipopolysaccharide components can significantly modify virulence factors by impacting protein localization and activity, providing insights into potential therapeutic targets for bacterial infections.
