Publications by authors named "Luisa Safar-Boueri"
Article Synopsis
- Immunosuppressive medications, while crucial for preventing graft rejection in organ transplants, can lead to complications such as cardiovascular and oncologic issues.
- Liver transplant recipients can achieve a state of immunotolerance that allows them to safely withdraw from immunosuppression, maintaining an effective immune response without risking graft injury.
- Clinical research is exploring biomarkers and predictors for identifying liver transplant patients who can withdraw immunosuppression safely, alongside developing pharmacological methods for those at high risk of rejection.
Background: Studies have documented AKI with high-grade proteinuria in patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. In some patients, biopsies have revealed collapsing glomerulopathy, a distinct form of glomerular injury that has been associated with other viruses, including HIV. Previous patient reports have described patients of African ancestry who developed nephrotic-range proteinuria and AKI early in the course of disease.
View Article and Find Full Text PDFMembranous nephropathy (MN) is an immune complex-mediated cause of the nephrotic syndrome that can occur in all age groups, from infants to the very elderly. However, nephrotic syndrome in children is more frequently caused by conditions such as minimal change disease or focal segmental glomerulosclerosis, and much less commonly by MN. While systemic conditions such as lupus or infections such as hepatitis B may more commonly be associated as secondary causes with MN in the younger population, primary or "idiopathic" MN has generally been considered a disease of adults.
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