Chronic exercise leads to antiaggregant, antioxidant and anti-inflammatory effects in heart failure patients.

Background: Heart failure (HF) patients are at an increased risk of thrombotic events. Here, we investigated the effects of exercise training on platelet function and factors involved in its modulation in HF.

Design And Methods: Thirty HF patients were randomized to 6 months of supervised exercise training or to a control group that remained sedentary.