Publications by authors named "Luisa Alfonsi"
Article Synopsis
- Gestational diabetes mellitus (GDM) is linked to both immediate obstetric issues and long-term cardiovascular risks, but its effects on platelet function have been underexplored compared to type-2 diabetes.
- The study compared 23 women with GDM to 23 healthy pregnant women, measuring various aspects of platelet reactivity and endothelial function at different stages of pregnancy and postpartum.
- Results indicated that women with GDM had increased platelet hyperreactivity and activation, especially towards the end of pregnancy, with some abnormalities persisting up to 8 weeks after delivery, along with signs of endothelial dysfunction.
Objective: To evaluate diagnostic accuracy of quantitative fetal fibronectin (qfFN) test in predicting preterm birth (PTB) risk <34 weeks' gestation or within 14 days from testing. We explored the predictive potential of the test in five-predefined PTB risk categories based on predefined qfFN thresholds (<10, 10-49, 50-199, 200-499 and ≥500 ng/mL).
Methods: Measurement of cervicovaginal qfFN with Rapid fFN 10Q System (Hologic) in 126 women with singleton pregnancy (23-33 weeks' gestation) reporting signs and symptoms indicative of preterm labour (PTL).