Publications by authors named "Luis Tamayo Lomas Lorenzo"
Transcriptomics reveals shared immunosuppressive landscapes in ventilator-associated lower respiratory tract infections (VA-LRTI) patients.
Ignacio Martin-Loeches Gustavo Sganzerla Martinez Alexis Garduno Rachel Cusack David Andaluz-Ojeda Luis Tamayo Lomas Lorenzo Lorenzo Socias Crespi
Expert Rev Anti Infect Ther
November 2023
Background: Ventilator-associated pneumonia (VAP) represents a transitory status of immunoparalysis, and we hypothesized that ventilator-associated tracheobronchitis (VAT) could share also some degree of immune response to a respiratory infection.
Research Design And Methods: A prospective observational study in five medical ICUs to evaluate immunological alterations of patients with VA-LRTI. Immunological gene expression profiles in the blood using whole transcriptome microarrays in the first 24 hours following diagnosis.