Publications by authors named "Luis Sergio Ronchi"
Article Synopsis
- - The study examined plasma levels of the chemokines CCL3 and CCL4 in patients with different clinical forms of chronic Chagas disease, focusing on those with and without left ventricular systolic dysfunction (LVSD).
- - It involved analyzing plasma samples from 75 patients using ELISA and Milliplex® MAP assay, confirming the T. cruzi infection.
- - Results showed no significant level differences of CCL3 and CCL4 between digestive and cardiac forms of Chagas disease, and found that while LVSD patients had higher chemokine levels, CCL3 and CCL4 do not seem to affect susceptibility to the disease forms or influence LVSD development.
Infect Genet Evol
November 2016
Article Synopsis
- - Chagas disease, caused by the parasite Trypanosoma cruzi, can lead to various health issues like heart problems and digestive tract complications, but the factors determining why some people are symptomatic and others are not remain unclear.
- - This study involved 339 adults with chronic Chagas disease and aimed to explore how different blood group systems (ABO, Secretor, and Lewis) might be linked to the disease’s clinical forms.
- - While no significant differences were found between patients and healthy controls for the blood group systems, the combination of B plus AB Secretor phenotypes was significantly more common in patients with megacolon and megaesophagus compared to those with A plus O Secretor phenotypes.
Arq Gastroenterol
April 2009
Article Synopsis
- The study investigates the rectoanal inhibitory reflex in patients with chagasic megacolon, which is often not observed due to inadequate air volume during tests.
- Researchers aimed to determine the necessary air volume to trigger this reflex and assess its occurrence in affected patients.
- Findings revealed that the reflex was present in 43.6% of the studied patients, using an average air volume of 196 mL for successful induction.
Dis Colon Rectum
October 2002
Article Synopsis
- Chagasic megacolon is a common condition in central Brazil that requires surgical intervention, but there is no clear best technique for treatment.*
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- A study involved 147 patients who underwent a new surgical method called rectosigmoidectomy with an ileal interposition from 1985 to 1995, with some limitations in follow-up data.*
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- The results showed a low rate of major complications and a unique advantage over other methods, marking this technique as an effective option with minimal risks and low recurrence of constipation.*
