Publications by authors named "Luis S Palazon"
Article Synopsis
- Cyclins are key proteins that regulate the cell cycle, with the cyclin A1 gene (Ccna1) specifically playing a crucial role in meiosis and spermatogenesis.
- The study utilized a LacZ reporter gene to investigate Ccna1 expression, revealing its presence in mouse pre-meiotic spermatocytes and certain brain regions.
- The expression of cyclin A1 is linked to male fertility in mice, with genetic background influencing the severity of infertility; knockout mice are sterile, while heterozygous mice exhibit reduced fertility, especially in inbred strains.
