Publications by authors named "Luis R Moscote Salazar"
Purpose Of Review: To evaluate the role of sedation vacations in optimizing patient outcomes and enhancing the quality of care in neurological intensive care units (ICUs). We discuss the importance of sedation management in neurocritical care, considering recent research findings and clinical guidelines.
Recent Findings: Recent studies have highlighted the significance of sedation interruption protocols in improving patient outcomes in the ICU setting.
Background: Hyperglycemia is associated with adverse outcomes in patent with traumatic brain injury. There is convincing evidence of the deleterious effects of early systemic hyperglycemia on neurological outcomes and guides management toward intensive glycemic control. The purpose of this systematic review and meta analysis is to evaluate and summarize the level of evidence on the role of glycemic control in traumatic brain injury.
View Article and Find Full Text PDFPolymorphous low-grade neuroepithelial tumor of the young (PLNTY) is considered one of the low-grade neuroepithelial tumors, as per the World Health Organization 2021 classification of brain tumors. First described in 2016, these morphologically variable tumors are characterized by oligodendroglioma-like cellular components, infiltrative growth patterns, and cluster of differentiation 34 immunopositivity. A literature search of the PubMed/MEDLINE, SCOPUS, ScienceDirect, and COCHRANE databases (from inception to 20th June 2022) was carried out to identify relevant studies.
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- - The study investigates how the position of the sciatic nerve (SN) in relation to the ischial spine (IS) may contribute to deep gluteal syndrome (DGS), a painful condition associated with gluteal neuropathies.
- - Researchers analyzed MRI scans of 15 surgical patients who had piriformis release and compared them with 30 control patients, finding that the SN was more closely positioned to the IS in those with DGS.
- - Results indicated that patients who underwent the surgery experienced significant pain relief, suggesting that proper SN-IS alignment could help identify individuals who might benefit from surgical treatment.
Calvarial haemangiomas are benign, vascular tumours of the skull involving parietal and frontal bones. Mostly these lesions remain asymptomatic, and present with cosmetic deformity, headache, uncommon neurological symptoms and reported as case reports and case series. The radiological appearance can range from sessile growing intradiploically to globular and the lesions may extend outwards or inwards after eroding the outer and inner tables of the skull.
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- The study investigates the link between D-dimer levels and stroke in cancer patients, highlighting that higher D-dimer levels may indicate the presence of cancer in stroke patients.
- A systematic review and meta-analysis were conducted, examining 495 articles, ultimately including six high-quality studies with 2,651 ischemic stroke patients (13.97% with cancer).
- Results show that stroke patients with active cancer had significantly higher D-dimer levels compared to those without cancer, suggesting D-dimer could be a useful biomarker for predicting cancer in stroke cases.
Objective: Deep gluteal syndrome is a clinical condition in which discomfort may arise due to the pathoanatomy of the subgluteal space. We conducted an anatomical exploration to categorize the relationship of the piriformis muscle, sciatic nerve (SN), and pudendal nerve (PN) to the ischial spine (IS) and sacrospinous ligament.
Methods: We analyzed 22 cadavers.
Neurological manifestations have been widely reported in adults with COVID-19, yet the extent of involvement among the pediatric population is currently poorly characterized. The objective of our systematic review is to evaluate the association of SARS-CoV-2 infection with neurological symptoms and neuroimaging manifestations in the pediatric population. A literature search of Cochrane Library; EBSCO CINAHL; Global Index Medicus; OVID AMED, Embase, Medline, PsychINFO; and Scopus was conducted in accordance with the Peer Review of Electronic Search Strategies form (October 1, 2019 to March 15, 2022).
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- The study examines the link between cocaine use and poor neurological outcomes in patients with aneurysmal subarachnoid hemorrhage (SAH) through a systematic review and meta-analysis of observational studies.
- Results show that cocaine users experience significantly worse overall outcomes, including higher mortality rates and neurological impairment compared to non-users, although risks for hydrocephalus and seizures were not elevated.
- The findings suggest that cocaine consumption increases the likelihood of vasospasm and other complications in patients suffering from aSAH, highlighting the serious impact of recreational drug use on health.
Objective: This study aims to identify the shortcomings and quality content of YouTube videos and its effectiveness as a source of patient information on pudendal neuralgia treatment.
Methods: A search was conducted on YouTube using the words "pudendal neuralgia physical therapy," "medications for pudendal neuralgia," "pudendal nerve block," "pudendal neuralgia surgery," and "alternative treatments for pudendal neuralgia." The results were analyzed based on the source, general descriptive statistics, the intended audience, and five content areas.
Background: The supraorbital approach is a modification of the traditional pterional approach, and it offers the benefits of a shorter skin incision and a smaller craniotomy than the pterional approach. The purpose of this systemic review study was to compare the two surgical approaches for raptured and unruptured anterior cerebral circulation aneurysms.
Methods: We searched PubMed, EMBASE, Cochrane Library, SCOPUS, and MEDLINE, up to August 2021, for published studies on the supraorbital vs pterional keyhole approach for anterior cerebral circulation aneurysms, and reviewers performed a brief qualitative descriptive analysis of both approaches.
Background: Neurological manifestations have been widely reported in adults with COVID-19, yet the extent of involvement among the pediatric population is currently poorly characterized. The objective of our systematic review is to evaluate the association of SARS-CoV-2 infection with neurological symptoms and neuroimaging manifestations in the pediatric population.
Methods: A literature search of Cochrane Library; EBSCO CINAHL; Global Index Medicus; OVID AMED, Embase, Medline, PsychINFO; and Scopus was conducted in accordance with the Peer Review of Electronic Search Strategies form (October 1, 2019 to March 15, 2022).
Objectives: The neutrophil-to-lymphocyte ratio (NLR) is a simple and routinely performed hematological parameter; however, studies on NLR as a prognostic tool in traumatic brain injury (TBI) have yielded contradictory results.
Materials And Methods: This systematic review and meta-analysis was conducted according to the Preferred Reporting Items in the Systematic Review and Meta-Analysis guidelines 2020. Electronic databases of PubMed, Cochrane Library, Web of Science, and Scopus were searched.
Article Synopsis
- The "time is brain" concept highlights the critical need for quick transfer of stroke patients to medical care, and using helicopter emergency medical services (HEMS) can speed up this process and potentially improve patient outcomes.
- A systematic review of 8 studies found that while HEMS did not significantly reduce mortality rates in stroke patients, it was associated with improved overall outcomes and a lower rate of poor neurological results compared to standard emergency transport.
- The research emphasizes that while HEMS may not impact mortality significantly, it correlates with better neurological results for stroke patients, indicating its value in emergency medical response.
Chronic subdural hematoma (cSDH) is one of the most studied clinical entities in the neurosurgical literature. Management of cSDH is complicated by its propensity to recurrence. Various factors for the development of recurrence of cSDH have been described in various clinical, epidemiological, and observational studies, yet the evidence available is limited.
View Article and Find Full Text PDFIntroduction: Evidence about predictors of poor outcomes such as cerebral infarction (CI) after aneurysmal subarachnoid hemorrhage (aSAH) has not been fully elucidated.
Evidence Acquisition: We performed a systematic review and meta-analysis on studies with adults with aSAH considering RCT and non-RCT, prospective, and retrospective cohort studies describing clinical, imaging as well as angiographic studies in patients with aSAH.
Evidence Synthesis: After reviewing the complete text, 11 studies were considered eligible, out of which four were ruled out.
Introduction: Necrosis or hemorrhage associated with pituitary tumors is an infrequent complication. The term pituitary apoplexy is related to the development of an inflammatory process that leads to irritation of the meningeal and periselar areas. Regardless of the mechanism (hemorrhage or infarction), the extent of the hemorrhage and necrosis will produce an increase in intraselar pressure which, in turn, will lead to a more or less pronounced compression of neighboring structures, thus explaining the broad spectrum clinical.
View Article and Find Full Text PDFLetter to the Editor. Latin American collaboration in international neurotrauma registries: a strategy from the academy.
J Neurosurg
September 2022