Cost-Effectiveness Analysis of Pharmacological Treatment for Adult Kidney Transplant Recipients in Colombia.

Objectives: To evaluate cost-effective pharmacological treatment in adult kidney transplant recipients from the perspective of the Colombian health system.

Methods: A decision tree model for the induction phase and a Markov model for the maintenance phase were built. A review of the clinical literature was conducted to extract probabilities, and the life-years were used as the outcome.

Images dataset of beef meat samples with different shelf life.

Three different cuts of meat samples: inside skirt, knuckles, and sirloin were picture captioned on the first and fifth day after purchase. From each type of meat cut, ten pictures were taken at the beginning and the end of the studied shelf life, obtaining 60 different images. The images were taken under control variables in a black acrylic cabin.

Germline DNA Repair Genes Pathogenic Variants Among Mexican Patients With Prostate Cancer.

Background: Early identification of germline mutation carriers may be relevant for the optimal management of prostate cancer and to inform cancer risk in relatives. However, population minorities have limited access to genetic testing. The aim of this study was to describe the frequency of DNA repair gene pathogenic variants (PVs) among Mexican men with prostate cancer referred for Genomic Cancer Risk Assessment and testing.

Estimating cost-effectiveness thresholds under a managed healthcare system: experiences from Colombia.

Like most of the world, low- and middle-income countries have faced a growing demand for new health technologies and higher budget constraints. It is necessary to have technical instruments to make decisions based on real-world evidence that allows maximization of the population's health with a limited budget. We estimated the supply-based cost-effectiveness elasticity, which was then used to determine the cost-effectiveness threshold for the healthcare system of Colombia, a middle-income country where multiple insurers, paid under capitation rules, manage the compulsory contributions of the citizens and government subsidies.

One-tissue compartment model for myocardial perfusion quantification with N-13 ammonia PET provides matching results: A cross-comparison between Carimas, FlowQuant, and PMOD.

Purpose: To cross-compare three software packages (SPs)-Carimas, FlowQuant, and PMOD-to quantify myocardial perfusion at global, regional, and segmental levels.

Materials And Methods: Stress N-13 ammonia PET scans of 48 patients with HCM were analyzed in three centers using Carimas, FlowQuant, and PMOD. Values agreed if they had an ICC > 0.

Many-Body Signatures of Collective Decay in Atomic Chains.

Fully inverted atoms placed at exactly the same location synchronize as they deexcite, and light is emitted in a burst (known as "Dicke's superradiance"). We investigate the role of finite interatomic separation on correlated decay in mesoscopic chains and provide an understanding in terms of collective jump operators. We show that the superradiant burst survives at small distances, despite Hamiltonian dipole-dipole interactions.

Immunosenescence profile and expression of the aging biomarker (p16) in testicular cancer survivors treated with chemotherapy.

Background: Cytotoxic chemotherapy can cure advanced germ cell tumors. Nevertheless, cancer treatment may induce cellular senescence and accelerate molecular aging. The aging process implies an increase of cells expressing p16 and changes in lymphocyte subpopulations.

Whipple disease diagnosed by enteroscopy: first case report in Colombia of an underdiagnosed disease and literature review.

Background: Whipple's disease is a rare systemic disease caused by a gram-positive bacillus called Tropheryma whipplei. First described in 1907 as an intestinal lipodystrophy with histological finding of vacuoles in the macrophages of the intestinal mucous. Usually the symptoms are localized according to the compromised organ.

Cocoa ingestion protects plasma lipids in healthy males against ex vivo oxidative conditions: A randomized clinical trial.

The effects of in vivo cocoa-based supplementation were studied as a preconditioning treatment for ex vivo acute oxidative conditions in a controlled randomized clinical trial. Subjects were 100 healthy young men at Universidad Industrial de Santander blinded to the intervention and divided into two groups: The intervention group (n = 50) receiving 30 g of cocoa powder and 50 g of dark chocolate/d for 1 week with the remaining subjects receiving placebo. Cocoa products preconditioning for 1 week resulted in modifications in the susceptibility of plasma lipids over ex vivo oxidative conditions with effects of i) a significant increase in the oxidative resistance of plasma lipids measured by dienes formation (4.

Spin-optomechanical coupling between light and a nanofiber torsional mode.

Light that carries linear or angular momentum can interact with a mechanical object, giving rise to optomechanical effects. In particular, a photon can transfer its intrinsic angular momentum to an object when the object either absorbs the photon or changes the photon polarization, as in an action/reaction force pair. Here, we demonstrate resonant driving of torsional mechanical modes of a single-mode tapered optical nanofiber using spin angular momentum.

Detection in Colombian Patients with a Diagnosis of Esophageal Achalasia.

Achalasia is a motility disorder of the esophagus that might be secondary to a chronic infection. Several studies have investigated esophageal achalasia in patients with Chagas disease (CD) in Latin America, but no related studies have been performed in Colombia. The goals of the present study were to determine the presence of anti- antibodies in patients with esophageal achalasia who visited a referral hospital in Bogotá, Colombia, and to detect the presence of the parasite and its discrete typing units (DTUs).

Cerebral toxoplasmosis in an MS patient receiving Fingolimod.

Multiple Sclerosis (MS) is an autoimmune disease in which lymphocytes target putative myelin antigens in the CNS, causing inflammation and neurodegeneration. Fingolimod (FTY720) is an immunosuppressive drug used as a second line therapy for relapsing forms of MS due to its safety profile and good response to treatment. Despite its safety, there are still concerns about the possibility of Fingolimod being linked to the development of opportunistic infections like disseminated varicella zoster infections and herpes simplex encephalitis.

Dynamics of trapped atoms around an optical nanofiber probed through polarimetry.

The evanescent field outside an optical nanofiber (ONF) can create optical traps for neutral atoms. We present a non-destructive method to characterize such trapping potentials. An off-resonance linearly polarized probe beam that propagates through the ONF experiences a slow axis of polarization produced by trapped atoms on opposite sides along the ONF.

Cost-Utility Analysis of Reconstruction Compared With Primary Amputation for Patients With Severe Lower Limb Trauma in Colombia.

Background: To establish, from the health system perspective, the cost-utility relationship of limb reconstruction compared with primary amputation for patients older than 32 years with grade IIIB and IIIC severe lower limb trauma in Colombia, S.A.

Methods: A Markov model was built including different short-term and long-term states that represent the main events that a patient could experience after a lower limb amputation or a reconstruction.

Cost-Effectiveness Analysis of the Use of a Prophylactic Antibiotic for Patients Undergoing Lower Limb Amputation due to Diabetes or Vascular Illness in Colombia.

Background: The use of a prophylactic antibiotic in an amputation surgery is a key element for the successful recovery of the patient. We aim to determine, from the perspective of the Colombian health system, the cost-effectiveness of administering a prophylactic antibiotic among patients undergoing lower limb amputation due to diabetes or vascular illness in Colombia.

Methods: A decision tree was constructed to compare the use and nonuse of a prophylactic antibiotic.

[Not Available].

Introduction: Ondansetron reduces hospitalization rates for diarrhea and vomiting in children, but is not yet routinely used.

Objective: To estimate from a social perspective the relative cost-effectiveness of ondansetron for the treatment of vomiting in children with gastroenteritis and at risk of dehydration in Colombia.

Methods: Cost-effectiveness analysis from a social perspective, including direct medical costs and costs for caregivers.

Risk factors associated with Chagas disease in pregnant women in Santander, a highly endemic Colombian area.

Objective: To determine the prevalence and risk factors associated with Chagas disease in pregnant women in an endemic area of Santander, Colombia.

Methods: Cross-sectional study included 23 municipalities of Santander, Colombia. Serological IFAT and ELISA tests were undertaken to detect IgG anti- Trypanosoma cruzi.

[Associated factors to availability and use of electronic media in children from preschool to 4th grade].

Introduction: The increased availability of electronic media has changed the behavior in children and young people by encouraging sedentary lifestile, with health effects from a very young age.

Objective: To characterize the availability and use of electronic media and its associated factors in children from preschool through 4 th grade.

Materials And Methods: A cross-sectional study with cluster sampling was carried out.

High incidence of tuberculosis, low sensitivity of current diagnostic scheme and prolonged culture positivity in four colombian prisons. A cohort study.

Objective: To determine the incidence of pulmonary tuberculosis (TB) in inmates, factors associated with TB, and the time to sputum smear and culture conversion during TB treatment.

Methods: Prospective cohort study. All prisoners with respiratory symptoms (RS) of any duration were evaluated.

[Reliability and convergent construct validity of the abridged development scale and a Spanish translation of the Neurosensory Motor Development Assessment].

Introduction: Motor development is the acquisition and evolution of motor skills; its evaluation allows detection of abnormalities and permits a suitable opportunity for bringing them to medical attention. Several instruments have been designed to characterize motor development in early childhood, among them the Neurosensory Motor Development Assessment test. In Colombia, studies on the psychometric properties have not been published on any of these tests.

[Incidence of and factors for non-compliance to antituberculous treatment].

Introduction: Tuberculosis is a public health problem. Non-compliance with treatment regimes increases morbidity-mortality, perpetuates transmission and generates bacterial resistance. It is necessary to know incidence and associated factors to non-compliance for performance interventions.

[The validity of a presumptive diagnosis of cutaneous leishmaniasis performed by community health workers in Colombia].

Objective: To validate a method for the presumptive diagnosis of cutaneous leishmaniasis based on the observation of clinical-epidemiological criteria, carried out by community health workers in three endemic municipalities in Santander, a department in northeastern Colombia.

Methods: This evaluation study of diagnostic technologies was based on a cross-sectional sampling of suspected cases of cutaneous leishmaniasis in the municipalities of Rionegro, El Playón, and Landázuri. After being trained, the community health workers carried out the presumptive diagnoses of cutaneous leishmaniasis between October 2004 and November 2005.

Prevalence and impact of cardiovascular risk factors in Bucaramanga, Colombia: results from the Countrywide Integrated Noncommunicable Disease Intervention Programme (CINDI/CARMEN) baseline survey.

Background: Although cardiovascular diseases are the main cause of death in the region, there are few data on the prevalence of cardiovascular risk factors in Latin American. We studied the distribution and impact of cardiovascular risk factors in Bucaramanga, Colombia.

Methods: We conducted a cross-sectional study in a random sample of 2989 subjects 15-64 years old.