Publications by authors named "Luis Oliveira E Silva"
Erratum to: Santos M, Oliveira e Silva LF, Kohler HF, et al. Health-Related Quality of Life Outcomes in Head and Neck Cancer: Results From a Prospective, Real-World Data Study With Brazilian Patients Treated With Intensity Modulated Radiation Therapy, Conformal and Conventional Radiation Techniques. Int J Radiat Oncol Biol Phys 2021;109:485-494.
Int J Radiat Oncol Biol Phys
February 2025
Purpose: This study aimed to identify the fluence smoothing threshold that preserves the dosimetric quality of planning for breast cancer intensity-modulated radiation therapy (IMRT).
Material And Methods: We conducted automated treatment planning for 60 breast cancer patients using the Eclipse Scripting Application Programming Interface. The plans included four-field IMRT, emphasizing smoothing weight combinations while maintaining a 4:3 aspect ratio between the X and Y directions.
Purposes: This study aimed to develop and validate algorithms for automating intensity modulated radiation therapy (IMRT) planning in breast cancer patients, with a focus on patient anatomical characteristics.
Material And Methods: We retrospectively selected 400 breast cancer patients without lymph node involvement for automated treatment planning. Automation was achieved using the Eclipse Scripting Application Programming Interface (ESAPI) integrated into the Eclipse Treatment Planning System.
Article Synopsis
- Limited resources for radiation therapy in Latin America have led to an interest in hypofractionated radiotherapy (HRT) as a time- and cost-efficient solution for cancer treatment.
- A panel of Latin American experts discussed key challenges to adopting HRT, including the absence of clinical guidelines, inadequate education and training for personnel, and high equipment costs.
- Recommendations were made to address these barriers, highlighting that increased HRT adoption could improve cancer treatment access and health outcomes in the region, and could also serve as a model for other countries facing similar issues.
Purpose: To compare global health-related quality of life (HRQoL) and overall survival (OS) in patients with head and neck cancer treated with intensity modulated radiation therapy (IMRT), conformal radiation therapy (3DCRT) or conventional radiation therapy (2DRT).
Methods And Materials: In this real-world, multi-institutional and prospective study, HRQoL outcomes were assessed using the European Organisation for Research and Treatment of Cancer Quality-of-life Questionnaire Core 30 (EORTC QLQ-C30) and European Organisation for Research and Treatment of Cancer Quality-of-life Questionnaire Head and Neck 43 (H&N43) questionnaires. Item response theory was used to generate a global HRQoL score, based on the 71 questions from both forms.