Analysis of the esthetic preferences of Spanish laypersons and dentists regarding the different width proportions of the maxillary anterior teeth.

Statement Of Problem: Multiple esthetic width proportions have been described for maxillary anterior teeth. However, the esthetic characteristics of each have not been compared simultaneously to determine which proportion is preferred by dentists and laypersons.

Purpose: The purpose of this study was to evaluate the preferences of dentists and laypersons with respect to internationally recognized dental esthetic proportions.

Clinical outcomes after the use of complete autologous oral mucosa equivalents: preliminary cases.

Objective: Previously, we reported how to obtain complete autologous oral mucosa equivalents (CAOMEs) composed of an autologous plasma scaffold and fibroblasts together with immature keratinocytes able to build an oral epithelium with a structure similar to that of the oral mucosa. In this study, we present the clinical outcomes after applying our CAOMEs as grafts.

Study Design: Four patients who needed a CAOME to restore a defect of oral mucosa were selected.

Use of autologous skin equivalents with artificial dermal matrix (integra) in donor site coverage in radial forearm free flaps: preliminary cases.

Purpose: The radial forearm flap is one of the most commonly used methods for intraoral reconstruction in oral carcinoma surgery. One of its disadvantages is the residual functional and unaesthetic defect in the donor site. The objective of this report is to describe preliminary cases of a novel method to cover such donor sites based on the use of autologous skin equivalents (ASEs) and an artificial dermal matrix (Integra, Prim, Barcelona, Spain).

Expression of Bcl-2 but not Bax has a prognostic significance in tongue carcinoma.

Background: Among the molecular mechanisms involved in carcinogenesis, defects in the regulation of programmed cell death (apoptosis) make important contributions to the pathogenesis and progression of cancer. Apoptosis regulatory genes include the antiapoptotic bcl-2 gene and the proapoptotic bax gene. The aim of this study was to determine the spectrum of Bax and Bcl-2 expression, and to correlate these findings with clinicopathologic variables and prognosis.