Novel 2-Aryloxazoline Compounds Exhibit an Inhibitory Effect on spp., Including Antifungal-Resistant Isolates.

Because of the increased resistance to currently available antifungals, fungal infections represent a significant challenge to human health. Herein, we report the synthesis of 2-aryloxazoline derivatives from the reaction between l-threonine and derivatives of salicylic or naphthoic acid. In total, 26 compounds were obtained and tested against species of , , and .