Publications by authors named "Luis Lopez Morillo"
X-ray multi-projection imaging (XMPI) is an emerging experimental technique for the acquisition of rotation-free, time-resolved, volumetric information on stochastic processes. The technique is developed for high-brilliance light-source facilities, aiming to address known limitations of state-of-the-art imaging methods in the acquisition of 4D sample information, linked to their need for sample rotation. XMPI relies on a beam-splitting scheme, that illuminates a sample from multiple, angularly spaced viewpoints, and employs fast, indirect, X-ray imaging detectors for the collection of the data.
View Article and Find Full Text PDFMS SPIDOC is a novel sample delivery system designed for single (isolated) particle imaging at X-ray Free-Electron Lasers that is adaptable towards most large-scale facility beamlines. Biological samples can range from small proteins to MDa particles. Following nano-electrospray ionization, ionic samples can be m/z-filtered and structurally separated before being oriented at the interaction zone.
View Article and Find Full Text PDFArticle Synopsis
- The European X-ray Free-Electron Laser (FEL), launched in May 2017, is the world's first high-repetition-rate hard X-ray FEL, enhancing biological structure determination through advanced serial crystallography.
- Its ability to perform experiments at significantly higher data rates allows for groundbreaking discoveries and access to complex experiments that weren’t possible with older systems.
- The paper details the SPB/SFX instrument's features, which support various techniques like serial crystallography and single particle imaging, as well as its current capabilities and future potential.