Publications by authors named "Luis Jose Muniz Rascado"

Article Synopsis
  • RegulonDB is a detailed online resource launched 20 years ago that tracks transcription regulation in E. coli K-12, using historical molecular biology and recent genomic data.
  • It curates research literature and includes data from ChIP and gSELEX experiments, estimating that only 10% to 30% of the gene regulatory interactions in E. coli are currently known.
  • The platform features a JBrowse for visualizing datasets, a Microbial Conditions Ontology for experiment reproducibility, and analyzes Genetic Sensory-Response Units for transcription factors, enhancing its biocuration with natural language processing techniques.
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Experimentally generated biological information needs to be organized and structured in order to become meaningful knowledge. However, the rate at which new information is being published makes manual curation increasingly unable to cope. Devising new curation strategies that leverage upon data mining and text analysis is, therefore, a promising avenue to help life science databases to cope with the deluge of novel information.

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