Publications by authors named "Luis Javier Lamuela-Calvo"

Article Synopsis
  • Percutaneous endoscopic gastrostomy (PEG) is a safe and effective way to provide nutrition for patients with malnutrition and swallowing difficulties, though not recommended for those with advanced cognitive decline.* -
  • A study of 648 patients from 2001 to 2019 found that 39.5% experienced complications, with the most common being bronchoaspiration and rupture/dysfunction.* -
  • Factors such as early complications, male gender, and older age were linked to a shorter survival time after PEG placement, while being female appeared to offer some protective benefits.*
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Introduction: the risk of hepatocellular carcinoma (HCC) after eradication of the hepatitis C virus (HCV) is highly variable in patients with advanced fibrosis (F3). Long-term surveillance for HCC after sustained virological response (SVR) is controversial in these patients. The objective of this study was to describe the post-SVR follow-up in clinical practice in patients with F3 and determine the predictive factors for the development of HCC.

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Background And Aims: Clinical trials and real-life studies with ustekinumab in Crohn's disease [CD] have revealed a good efficacy and safety profile. However, these data are scarcely available in elderly patients. Therefore, we aim to assess the effectiveness and safety of ustekinumab in elderly patients with CD.

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We present the case of a 37-year-old Caucasian woman, with no history of interest, who came to the emergency room for an occlusive condition of 24 hours' evolution. The patient reported a weight loss of 12 kg in the last month, as well as the appearance of a lump in the left breast in the last week. A chest-abdominal CT scan revealed multiple solid-appearing nodules in the left breast, a metastatic liver lesion, and a tumor-like mass in the right iliac fossa measuring 90x60 mm.

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We present the case of a 38-year-old man with no previous medical history who went to the emergency department due to abdominal pain and diarrheal stools with blood of 24 hours of evolution. The patient reports consumption of anti-inflammatories the previous days due to back pain.

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Article Synopsis
  • A study was conducted to evaluate the long-term effects of stopping anti-TNF treatment in patients with inflammatory bowel disease (IBD), focusing on relapse rates after discontinuation during clinical remission.
  • The study involved 1,055 patients and revealed a 12% yearly relapse rate, with 50% experiencing a relapse within five years, while many managed to regain remission after retreatment or switching therapies.
  • Overall, the findings suggest that while many patients remain in remission post-discontinuation, retreatment with the same anti-TNF is often effective for those who relapse, and alternative therapies can also lead to remission in non-responders.
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