Publications by authors named "Luis Javier Jara Quezada"
Article Synopsis
- The update of the Mexican Guidelines for the Treatment of Systemic Lupus Erythematosus has been developed with input from various experts across the country.
- The new guidelines follow the GRADE system, which helps in evaluating the quality of evidence for healthcare recommendations.
- Key new topics included in the update are vaccines, pregnancy, and cardiovascular risk, which were not addressed in the previous guidelines from 2017.
Antiphospholipid antibody syndrome (usually named antiphospholipid syndrome, APS) is an autoimmune disorder seen mainly in young people. Clinically, APS is described by pregnancy complications and/or a hypercoagulable state, including the venous or arterial vasculature, and strongly related to antiphospholipid antibodies. Although several cardiac manifestations have been involved with APS, and accelerated atherosclerosis is present in this condition, little is known about cardiovascular (CV) risk and the relation between APS.
View Article and Find Full Text PDFBackground: COVID-19 brought with it unknowns related to systemic sclerosis.
Objective: To know the clinical evolution and prognosis of COVID-19 in a cohort of patients with systemic sclerosis.
Methods: During the pandemic, we had digital contact with a cohort of 197 patients with SSc.
Article Synopsis
- The study investigates whether blood groups (BG) influence susceptibility to SARS-CoV-2 infection among healthcare workers prior to vaccination.
- Using a cross-sectional design, researchers compared the blood groups, antibody presence, and symptoms of 102 convalescent health workers against 116 controls from March to June 2020.
- Results indicated that blood group O was the most common among both groups, with a non-significant lower risk of infection associated with BG-O and a potential higher risk for BG-A, while 15% of the convalescent group did not develop antibodies post-infection.
The present document is a position statement of the Mexican College of Rheumatology on the use of biosimilars in rheumatic diseases. This position considers that biosimilars should be considered as interchangeable, that automatic substitution without previous notice in stable patients during follow-up is not ethical, that the approval of a biosimilar should only be given after exhaustive review of preclinical and clinical data marked by Mexican regulations, that it should be clearly stated in the nomenclature of biologic drugs which is the innovator and which is the biosimilar, that it is not correct to choose a biosimilar as treatment based only on economic reasons or extrapolate indications based only on the approval of the innovator and in the absence of safety and efficacy data for the biosimilar.
View Article and Find Full Text PDFThe method used to set the pass mark in an objective structured clinical examination defines the performance of candidates for certification as rheumatologists.
Reumatol Clin (Engl Ed)
May 2019
Background: The Mexican Accreditation Council for Rheumatology certifies trainees (TR) on an annual basis using both a multiple-choice question (MCQ) test and an objective structured clinical examination (OSCE). For 2013 and 2014, the OSCE pass mark (PM) was set by criterion referencing as ≥6 (CPM), whereas overall rating of borderline performance method (BPM) was added for 2015 and 2016 accreditations. We compared OSCE TR performance according to CPM and BPM, and examined whether correlations between MCQ and OSCE were affected by PM.
View Article and Find Full Text PDFIntroduction: Health staff self-applied strategies are insufficiently to reduce cardiovascular risk factors. The aim of this article is to investigate the prevalence of overweight, obesity and metabolic syndrome and waist/height index on health staff.
Methods: This is a cross-sectional study from January to April 2014 in 735 workers of the UMAE Specialties La Raza.
Clinical practice guidelines for the management of pregnancy in women with autoimmune rheumatic diseases of the Mexican College of Rheumatology. Part II.
Reumatol Clin
December 2016
Background: Pregnancy in women with autoimmune rheumatic diseases is associated with several maternal and fetal complications. The development of clinical practice guidelines with the best available scientific evidence may help standardize the care of these patients.
Objectives: To provide recommendations regarding prenatal care, treatment, and a more effective monitoring of pregnancy in women with lupus erythematosus, rheumatoid arthritis (RA) and antiphospholipid syndrome (APS).
Clinical practice guidelines for the management of pregnancy in women with autoimmune rheumatic diseases of the Mexican College of Rheumatology. Part I.
Reumatol Clin
December 2016
Background: Pregnancy in women with autoimmune rheumatic diseases is associated with several maternal and fetal complications. The development of clinical practice guidelines with the best available scientific evidence may help standardize the care of these patients.
Objectives: To provide recommendations regarding prenatal care, treatment, and a more effective monitoring of pregnancy in women with lupus erythematosus (SLE), rheumatoid arthritis (RA) and antiphospholipid antibody syndrome (APS).
Objective: To assess reliability and validity of the objectively-structured clinical examination (OSCE) applied in postgraduate certification processes by the Mexican Board of Rheumatology.
Method: Thirty-two (2013) and 38 (2014) Rheumatology trainees (RTs) underwent an OSCE consisting of 12 and 15 stations respectively, scored according to a validated check-list, as well as 300-multiple-choice 300 question examination (MCQ). Previously, 3 certified rheumatologists underwent a pilot-OSCE.