Coffee leaf rust (CLR) is caused by the biotrophic fungus Berk. & Br., a disease of economic importance, reducing coffee yield up to 60%.
View Article and Find Full Text PDFPhage therapy is a promising alternative to control bacterial diseases and the increasing problem of antibiotic resistance. In this sense, this research evaluates the viability of lyophilized vibrio phage vB_Pd_PDCC-1 using trehalose as a preservative excipient at different concentrations (4, 2, 1, and 0.5% w/v) and its potential for phage therapy application against a pathogenic bacteria Vibrio diabolicus in brine shrimp nauplii (Artemia franciscana).
View Article and Find Full Text PDFNanovaccine development is a growing research field in which the development of new carriers and bioconjugation approaches is a priority. In this sense, this report describes for the first time, the development of a novel conjugate that consists of gold nanoparticles (AuNPs) obtained by a one-step synthesis using an immunogenic peptide of the Lipopolysaccharide-assembly protein LptD frombacteria as a reducing and capping agent. The resultingcompounds were fully characterized and the results showed the high capacity of the peptide to form complexes and reduce gold ions.
View Article and Find Full Text PDFMollusk shell is composed of two CaCO3 polymorphs (calcite and aragonite) and an organic matrix that consists of acetic acid- or ethylenediaminetetraacetic acid (EDTA)-soluble and insoluble proteins and other biomolecules (polysaccharides, β-chitin). However, the shell matrix proteins involved in nacre formation are not fully known. Thus, the aim of this study was to identify and characterize a novel protein from the acetic acid-insoluble fraction from the shell of Pteria sterna, named in this study as Ps19, to have a better understanding of the biomineralization process.
View Article and Find Full Text PDF: The development of more efficacious vaccines, especially subunit vaccines administered via non-invasive routes, is a priority in vaccinology. Nanogels are materials that can meet the requirements to serve as efficient vaccine delivery vehicles (in terms of thermo-sensitivity, biocompatibility, and pH-responsiveness; among others); thus there is a growing interest in exploring the potential of nanogels for vaccine development. : Herein, a critical analysis of nanogel synthesis methodologies is presented and nanogel-based vaccines under development are summarized and placed in perspective.
View Article and Find Full Text PDFThis study reports biosynthesis of gold-nanoparticles (AuNPs) by using β-d-glucans isolated from the yeast Yarrowia lypolitica D1. β-d-glucans serve as reducing and stabilizing mediators that induce the formation of AuNPs on the outer surface of the own β-d-glucan. The systems were physicochemically characterized by ultraviolet visible (UV-Vis) spectroscopy, high-resolution transmission electron microscopy (HR-TEM), scanning electron microscope (SEM), energy-dispersive X-ray spectroscopy (EDS), and dynamic light scattering (DLS) analyses.
View Article and Find Full Text PDFMgBO doped with rare earths and alkaline elements has been reported as a good TLD because of its high sensitivity, effective atomic number close to that of biological tissue and low fading. In this work, thermoluminescent matrices were synthesized of MgBO:Dy and MgBO:Dy, Na to evaluate their thermoluminescent response (TL) when exposed to γ-rays and neutrons. The amount of Dy was studied in a concentration range of 0.
View Article and Find Full Text PDFThe ambient dose equivalent has been measured on the walls of a bunker with a 6 MV TomoLINAC, which was designed to have a conventional 18 MV LINAC. The ambient dose equivalent is due to scattered photons on patient bodies during cancer treatment. Measurements were carried out with thermoluminescent dosimeters that were fixed, at the isocentre plane, on the primary and secondary barriers, the maze, and on the TomoLINAC surface.
View Article and Find Full Text PDFJ Biomed Mater Res B Appl Biomater
April 2017
Research on nanometer-sized luminescent semiconductors and their biological applications in detectors and contrasting agents is an emergent field in nanotechnology. When new nanosize technologies are developed for human health applications, their interaction with biological systems should be studied in depth. Rare-earth elements are used in medical and industrial applications, but their toxic effects are not known.
View Article and Find Full Text PDFA rhodamine organosilane derivative (Rh-UTES) has been obtained by one-pot synthesis. The chemical structure of Rh-UTES was confirmed by nuclear magnetic resonance (NMR) and infrared (FTIR) techniques. To obtain an inorganic-organic hybrid sensor, Rh-UTES was covalently immobilized on a porous silicon microcavity (PSiMc) via triethoxysilane groups.
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