Background: Aneurysm repair using endovascular techniques has grown in importance as materials have improved. Studies of endovascular prostheses require experimental models that reproduce anatomic and pathophysiological characteristics of human aneurysms.
Objectives: To describe a porcine model of abdominal aortic aneurysm.
Purpose: To compare aortic intimal thickening of normal and hyperhomocysteinemic pigs (induced with a methionine-rich diet) following placement of a self-expanding nitinol stent.
Methods: Eighteen Macau pigs were used. They were older than eight weeks in age and had an average weight of 30 kg.