Premature rupture of membranes - A cause of foetal complications among lupus: A cohort study, systematic review and meta-analysis.

Objective: The present study aimed to analyse the frequency of premature rupture of membranes (PROMs) among 190 women with systemic lupus erythematosus (SLE) followed up at the Hospital Universitário Pedro Ernesto from 2011 to 2018 and to review the literature on PROM in patients with SLE.

Methods: A cohort study of SLE patients was conducted by analysing the following variables: sociodemographic characteristics, clinical manifestations of lupus, modified disease activity index for pregnancy, drugs used during pregnancy, intercurrent maternal infections and obstetric outcomes. Additionally, seven electronic databases (PubMed, Embase, Cochrane, Scielo, Scielo Brazil, Virtual Health Library Regional Portal and Google Scholar) were systematically searched.

Evaluation of the adequacy of reference charts for the accurate identification of fetuses with bone length below the 5th percentile.

Aim: To identify reference charts for femoral and humeral lengths enabling appropriate identification of fetuses <5th percentile in one population.

Methods: Two samples of fetuses aged 14-40 weeks were selected from our institution's ultrasonographic database. Regression analysis was used to construct reference charts of femoral and humeral lengths based on the local population (n=901).