Int J Psychophysiol
June 2015
Major depressive disorder (MDD) is recurrent, and its pathophysiology is not fully understood. Studies using electric tomography (ET) have identified abnormalities in the current density (CD) of MDD subjects in regions associated with the neurobiology of MDD, such as the anterior cingulate cortex (ACC) and medial orbitofrontal cortex (mOFC). However, little is known regarding the long-term CD changes in MDD subjects who respond to antidepressants.
View Article and Find Full Text PDFObjective: Longitudinal magnetic resonance imaging (MRI) studies have shown reduced cortical thickness (CT) in individuals with ADHD, but this abnormality disappears with age, suggesting developmental delay. However, cross-sectional MRI studies have shown reduced CT, suggesting abnormal development. The aim of this study was to compare whole-brain CT in male and female children, adolescents, and adults with ADHD with whole-brain CT in matched control participants.
View Article and Find Full Text PDFBackground: MRI studies have shown a decreased cerebellum volume in individuals with ADHD. However, most of these studies were conducted with male children, many of whom were medicated with stimulants. As such, unmedicated, non-White girls are underrepresented in such MRI studies.
View Article and Find Full Text PDFBackground: Magnetic resonance imaging (MRI) studies have shown decreased caudate volumes in individuals with attention deficit hyperactivity disorder (ADHD). However, most of these studies have been carried out in male children. Very little research has been done in adults, and the results obtained in children are difficult to extrapolate to adults.
View Article and Find Full Text PDFObjective: The prevalence of ADHD in the general adult population has been estimated to be about 4.4%. However, few studies exist in which the prevalence of ADHD in psychiatric adult outpatient samples has been estimated.
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