Publications by authors named "Luis Getino"
Testosterone holds significant medical and economic importance, with the global market for testosterone replacement therapies valued at approximately USD 1.9 billion in 2023. This hormone is essential for the development and maintenance of male sexual characteristics as well as bone and muscle health.
View Article and Find Full Text PDFArticle Synopsis
- - The search for eco-friendly alternatives to traditional plastics has led to increased interest in bio-based polymers known as polyhydroxyalkanoates (PHAs), which are viewed as healthier for the environment.
- - PHAs are natural polymers produced by various microorganisms and can be created using agroindustrial waste like cacao shells and cheese whey, presenting potential for sustainable production methods.
- - Despite the promising benefits of using waste materials to produce PHAs, there are challenges in improving the efficiency and cost-effectiveness of these production processes, highlighting the necessity for ongoing research and development.
Article Synopsis
- - Strain U can utilize biogenic amines like putrescine and cadaverine, along with their breakdown products (ɣ-aminobutyrate and δ-aminovalerate), as its only carbon sources.
- - Several gene paralogs have been identified in strain U that are responsible for catabolizing these compounds, including those encoding putrescine-pyruvate and ɣ-aminobutyrate aminotransferases.
- - Gene expression levels vary significantly based on the carbon source; putrescine upregulates certain genes while cadaverine triggers others, highlighting distinct mechanisms for polyamine metabolism in strain U.
Interest about the isolation and characterization of steroid-catabolizing bacteria has increased over time due to the massive release of these recalcitrant compounds and their deleterious effects or their biotransformation derivatives as endocrine disruptors for wildlife, as well as their potential use in biotechnological approaches for the synthesis of pharmacological compounds. Thus, in this chapter, an isolation protocol to select environmental bacteria able to degrade sterols, bile acids, and androgens is shown. Moreover, procedures for the determination of cholesterol oxidase or different hydroxysteroid dehydrogenase activities in Pseudomonas putida DOC21, Rhodococcus sp.
View Article and Find Full Text PDFXerotolerance: A New Property in Genus.
Microorganisms
November 2021
The highly xerotolerant bacterium classified as sp. Helios isolated from a solar panel in Spain showed a close relationship to 255-15 isolated from Siberian permafrost. Xerotolerance has not been previously described as a characteristic of the extremely diverse genus, but both strains Helios and 255-15 showed higher xerotolerance than that described in the reference xerotolerant model strain .
View Article and Find Full Text PDF