Publications by authors named "Luis Garcia-Sancho"
Thyroid dysfunctions are common in chronic hepatitis C virus (HCV) infection. HCV-RNA has been detected by reverse-transcription polymerase chain reaction (PCR) in thyroid from HCV infected patients with acquired immunodeficiency syndrome. However, morphological evidence of HCV replication in thyroid cells from immune competent patients has not been provided.
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- - The study examined T lymphocytes from gastric cancer patients using a specific virus transformation technique to create T-cell lines for analysis of their function and characteristics.
- - Results showed that these T cells had significantly lower responses to stimulation from certain antibodies and interleukins compared to healthy controls, indicating impaired function in the cancer patients.
- - The findings suggest that dysfunctional mucosal T lymphocytes in gastric adenocarcinoma patients may hinder the body's ability to control tumor growth effectively.
Background: Obesity constitutes a clear risk factor for cholelithiasis, especially if it is associated with a rapid weight loss, as is the case of patients following bariatric surgery. Prophylactic cholecystectomy is indicated in biliopancreatic diversions due to the high incidence of postoperative cholelithiasis. However, there is no agreement on gastric bypass.
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- A study on 25 patients with resectable gastric adenocarcinoma illustrated differences in immune response between patients with and without residual neoplastic disease (RND- vs. RND+).
- Both patient groups had significantly fewer CD3-expressing cells compared to healthy individuals, indicating a compromised immune response.
- The reduced expression of CD45 and poor proliferation of immune cells in RND+ patients may serve as indicators for faster disease progression and could help in determining the need for more aggressive treatment options.
Background And Aims: Rectovaginal fistulas in patients with Crohn's disease are difficult to resolve, and surgical failure is very frequent. Recent studies have shown that adult stem cells extracted from certain tissues, such as adipose tissue, can develop into different tissues, such as muscle.
Patient And Methods: We report here the case of a young patient with Crohn's disease who had a recurrent rectovaginal fistula that was treated by autologous stem-cell transplantation with a lipoaspirate as the source of stem cells.