Publications by authors named "Luis Florez"

Background: Ticks are obligate hematophagous ectoparasites involved in transmitting viruses of public health importance. The objective of this work was to identify the Jingmen tick virus in hard ticks from the Colombian Caribbean, an arbovirus of importance for public health.

Methods: Ticks were collected in rural areas of Córdoba and Cesar, Colombia.

View Article and Find Full Text PDF

The Pan American Health Organization has been committed to training physicians in leadership competencies since 2008. However, four reviews on teaching leadership using competency-based education in undergraduate medical education (UME) identified only two of 35 MS: Canada and the USA. Previous reviews did not use a systemic approach or qualitative methodology to explore factors influencing leadership education.

View Article and Find Full Text PDF
Article Synopsis
  • - The study investigated the effectiveness of using closed face shields along with surgical masks to reduce the transmission of COVID-19 (SARS-CoV-2) among working adults in Bogotá, Colombia during the pandemic.
  • - Participants were randomly divided into two groups: one wore closed face shields with surgical masks while the other group wore only surgical masks, and the primary outcome assessed was the rate of positive COVID-19 test results over a follow-up period of 21 days.
  • - Results showed that the closed face shield plus surgical mask combination was not less effective than using just a surgical mask, with very low rates of infection in both groups, suggesting that this method could be suitable for high-risk settings.
View Article and Find Full Text PDF

Extracellular vesicles (EVs) are biological nanoparticles of great interest as novel sources of biomarkers and as drug delivery systems for personalized therapies. The research in the field and clinical applications require rapid quantification. In this study, we have developed a novel lateral flow immunoassay (LFIA) system based on FeO nanozymes for extracellular vesicle (EV) detection.

View Article and Find Full Text PDF

The canine transmissible venereal tumor (CTVT) is a transplantable cancer with the ability evade the immune system, despite strict immune surveillance of the host; in this context, the relationship between inflammatory infiltrate and CTVT prognosis is not entirely understood. Natural canine transmissible venereal tumors of 22 dogs were evaluated for tumor/host interaction through clinical and epidemiological data, cyto-histopathological and cytogenetic findings and, mainly, cell-mediated immune response. We performed analysis on dogs with naturally acquired disease to provide information from the study of CTVT biology in its natural course, as the clinical evolution of the natural tumor in the host is not yet as well known as in the laboratory.

View Article and Find Full Text PDF

Background: Epidemiologic surveillance of COVID-19 is essential to collect and analyse data to improve public health decision making during the pandemic. There are few initiatives led by public-private alliances in Colombia and Latin America. The CoVIDA project contributed with RT-PCR tests for SARS-CoV-2 in mild or asymptomatic populations in Bogotá.

View Article and Find Full Text PDF

Background: In 2010, 240 billion US dollars was invested worldwide to conduct research for health; unfortunately, 200 billion was misused in the production and reporting of the evidence researched. Universities could facilitate students to acquire leadership competencies to move well-conducted research findings into practical use; this could be an essential move to reduce the misuse of investment.

Methods: A literature review was done based on the Equator Network and Cochrane guidelines, followed by three Delphi rounds to select competencies.

View Article and Find Full Text PDF

The data in this article includes biotechnological joint patents as a proxy of technological alliances. Joint patents are not directly found in public or commercial databases. Each joint patent has their corresponding International Patent Classification codes, their forward citation measure as an indicator of innovation value, and the firms involved in the process.

View Article and Find Full Text PDF

Mental health law in Colombia has evolved over the past 50 years, in concert with worldwide recognition and prioritisation of mental healthcare. Laws and policies have become increasingly sophisticated to accommodate the ongoing transformations throughout Colombia's healthcare system and improvements in mental health screening, treatment and supportive care. Mental health law and policy development have been informed by epidemiological data on patterns of mental disorders in Colombia.

View Article and Find Full Text PDF

Programs that provide services for internally displaced persons (IDPs) in Colombia, South America face challenges when attempting to engage and enroll the target population of forced migrants they intend to serve. Innovative multi-strategy outreach approaches must be used in order to effectively seek, recruit, provide services, monitor, and retain IDPs.

View Article and Find Full Text PDF

This commentary aims to delineate the distinguishing features of conflict-induced internal displacement in the nation of Colombia, South America. Even as Colombia is currently implementing a spectrum of legal, social, economic, and health programs for "victims of armed conflict," with particular focus on internally displaced persons (IDPs), the dynamics of forced migration on a mass scale within this country are little known beyond national borders.   The authors of this commentary are embarking on a global mental health research program in Bogota, Colombia to define best practices for reaching the displaced population and implementing sustainable, evidence-based screening and intervention for common mental disorders.

View Article and Find Full Text PDF

This study searched for mutations in the MLH1 and MSH2 genes in 23 unrelated Colombian families with suspected hereditary nonpolyposis colorectal cancer (HNPCC). The families were grouped according to the fulfillment of the Amsterdam II criteria or the Bethesda guidelines. We screened all probands by single-strand conformational polymorphism (SSCP) and direct DNA sequencing.

View Article and Find Full Text PDF