This retrospective, multicenter observational study aimed to describe the outcomes of surgical and medical treatment of -related prosthetic joint infection (PJI) and the potential benefit of rifampin-based therapies. Patients with -related PJI who were diagnosed and treated between January 2003 and December 2016 were included. We analyzed 44 patients with -related PJI (median age, 67.
View Article and Find Full Text PDFObjectives: To compare the characteristics and outcomes of cases with acute prosthetic joint infection (PJI; early post-surgical or hematogenous) by managed with implant removal (IRm) or debridement and retention (DAIR). To analyze the outcomes of all cases managed with IRm (initially or after DAIR failure).
Methods: Retrospective, multicenter, cohort study of PJI by (2003-2010).
Thiscase report concerns a 34-year-old male with a hip prosthesis infection, under treatment with antidepressant and antihypertensive drugs, who presented with an increase in blood pressure after four days of treatment with oral tedizolid. Tedizolid was discontinued, and the dose of antihypertensive was increased. The patient progressively achieved the normalisation of blood pressure values, which allowed a reduction in the antihypertensive agent dose to its usual regimen.
View Article and Find Full Text PDFLevofloxacin plus rifampicin (L+R) is the treatment of choice for acute staphylococcal prosthetic joint infection (PJI) managed with debridement and implant retention (DAIR). Long courses have been empirically recommended, but some studies have suggested that shorter treatments could be as effective. Our aim was to prove that a short treatment schedule was non-inferior to the standard long schedule.
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